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CDK1 抗体

This 小鼠 单克隆 antibody specifically detects CDK1 in WB, IF, IP 和 IHC (p). It exhibits reactivity toward 人 和 Cow.It has been mentioned in 1 publication
产品编号 ABIN114583
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDK1 抗体 (ABIN114583)

抗原

See all CDK1 抗体
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

适用

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人, Cow

宿主

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小鼠

克隆类型

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单克隆

标记

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This CDK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

POH-1
  • 特异性

    The antibody POH-1 specifically detects Cdk1 (p34Cdc2). Staining of Cdk1 reflects the proliferating potential of respective tissue.

    交叉反应 (详细)

    Species reactivity (tested):Human, Non-Human Primates, Bovine.

    纯化方法

    Affinity Chromatography on Protein A.

    免疫原

    Recombinant human cdc2 protein.

    亚型

    IgG2a
  • 应用备注

    Western Blot. Immunoprecipitation. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Jaeger, Koczan, Thiesen, Ibrahim, Gross, Spang, Kunz: "Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 3, pp. 806-15, (2007) (PubMed).

  • 抗原

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    别名

    CDK1

    背景

    The p34cdc2 is a 34 kDa phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the cell cycle. Expression of p34cdc2 reflects the proliferating potential of positively staining tissue. The maximal activity of p34cdc2 is achieved when it is fully dephosphorylated. It is a 34kD catalytic subunit of maturation promoting factor (MPF) and complexes with both cyclin A and cyclin B in mammalian cells.Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase

    基因ID

    983

    NCBI登录号

    NP_001777

    UniProt

    P06493

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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