ITM2B 抗体
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北京 101111
Quick Overview for ITM2B 抗体 (ABIN113338)
抗原
See all ITM2B 抗体适用
宿主
克隆类型
标记
应用范围
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序列
- CSRTVKKNII EEN
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特异性
- The antibody recognizes the typical amyloid deposits in brains of patients suffering from the disease. This antibody has been developed against the carboxy terminal extracellular sequence of the mutated BRI protein.
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纯化方法
- Affinity chromatography.
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免疫原
- Peptide coupled to carrier protein.
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anti-Integral Membrane Protein 2B (ITM2B) (Internal Region) antibody
Verified ITM2B 适用: 人 ELISA, WB, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 81-148) antibodyITM2B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 1-266) antibodyITM2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 146-245) antibodyITM2B 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 1-266) antibodyITM2B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) antibodyITM2B 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Integral Membrane Protein 2B (ITM2B) (AA 218-247), (C-Term) antibodyITM2B 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32712 unconjugated
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应用备注
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Suitable for Immunohistochemistry on frozen sections. Suggested positive control: pathological brain sections. (Not recommended in Western blots).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg /ml
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缓冲液
- PBS, pH 7.2, containing 0.09 % sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2-8 °C (Lyophilized) or reconstituted in small aliquots at -20 °C.
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- ITM2B (Integral Membrane Protein 2B (ITM2B))
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别名
- ITM2B
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背景
- The mutated BRI protein (ITM2B) was identified in patients with familial British dementia. The unusual 277 residue precursor protein releases a 34-residue amyloidogenic peptide by the action of the protease furin, leading to the deposition of a protein fragment that seems to be involved in the pathogenesis of familial British dementia.Synonyms: BRI, BRI2, ITM2B, Integral membrane protein 2B, Transmembrane protein BRI
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基因ID
- 9445
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NCBI登录号
- NP_068839
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UniProt
- Q9Y287
抗原
-
