CX3CL1 抗体 (C-Term)
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Quick Overview for CX3CL1 抗体 (C-Term) (ABIN113336)
抗原
See all CX3CL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- The antibody reacts with Fractalkine.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity purified against peptide coupled to Sepharose
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免疫原
- Synthetic C-terminal peptide coupled to carrier protein Remarks: The immunizing sequence is > 90% identical with the corresponding mouse and rat sequences.
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应用备注
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Immunohistochemistry on frozen sections: 1 μg/mL (1: 200). Lower working concentrationcombined with longer incubation time (e. g. > 2 hours at room temperature) and choice ofblocking reagent and secondary antibody may improve your results. Recommended positive control: Rat brain
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 0.5 mL distilled water to make stock solution.
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2 containing 0.01 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- Store at 2-8 °C after reconstitution.
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- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
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别名
- Fractalkine / CX3CL1
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背景
- Fractalkine is a chemokine present in endothelial cells from several tissues, including brain, liver, and kidney. A high level of fractalkine has also been described in neurons from different regions of the mouse brain. It is the only member of the CX(3)C class of chemokines. Fractalkine contains a chemokine domain (CDF) attached to a membranespanning domain via a mucin-like stalk. However, fractalkine can also be proteolytically cleaved from its membrane-spanning domain to release a freely diffusible form. Fractalkine attracts and immobilizes leukocytes by binding to its receptor, CX(3)CR(1).Synonyms: C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, FKN, NTT, Neurotactin, SCYD1, Small-inducible cytokine D1
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基因ID
- 6376
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NCBI登录号
- NP_002987
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UniProt
- P78423
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途径
- Synaptic Membrane
抗原
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