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Ceruloplasmin 抗体

This anti-Ceruloplasmin antibody is a 绵羊 多克隆 antibody detecting Ceruloplasmin in EIA 和 IHC (fro). Suitable for 人.
产品编号 ABIN113276
发货至: 中国

Quick Overview for Ceruloplasmin 抗体 (ABIN113276)

抗原

See all Ceruloplasmin (CP) 抗体
Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

适用

  • 55
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宿主

  • 49
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  • 1
绵羊

克隆类型

  • 56
  • 9
多克隆

标记

  • 40
  • 10
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This Ceruloplasmin antibody is un-conjugated

应用范围

  • 45
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  • 11
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Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    Recognizes Ceruloplasmin. This antibody shows minimal reactivity with related serum proteins.

    纯化方法

    Ammonium Sulphate Fractionation

    免疫原

    Native human Ceruloplasmin
  • 应用备注

    Immunohistochemistry on Frozen Sections (1/20-1/200). ELISA (Has been used at dilutions as high as 1/400K in a simple ELISA with 0.1 μ/wellcoated).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    5.0 mg/mL

    缓冲液

    PBS, pH 7.2 contaioning 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

    别名

    Ceruloplasmin

    背景

    Ceruloplasmin is a copper binding plasma glycoprotein consisting of a single polypeptide chain. It has a molecular weight of 132 kDa and occurs in plasma at a concentration of 150-500 mg/L. Although the physiological functions of Caeruloplasmin are not fully understood it is implicated in a number of possible functions. 95 % of plasma copper is bound to Caeruloplasmin, implying some involvement in copper transport. Caeruloplasmin has been described as both an oxidant and an antioxidant, its exact role or roles in this respect are not clear. Plasma levels of Caeruloplasmin are elevated after inflammation and trauma and it is therefore classified as an acute phase protein. The measurement of Caeruloplasmin in plasma is useful in the diagnosis of Wilson's disease, where levels are greatly reduced. Ceruloplasmin is extremely labile in plasma and rapidly degrades to 115 kDa and 19 kDa fragments. The age of plasma samples should therefore be taken into account when interpreting immunological analysis of ceruloplasmin.Synonyms: CP, Ferroxidase

    基因ID

    1356

    NCBI登录号

    NP_000087

    UniProt

    P00450

    途径

    Transition Metal Ion Homeostasis
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