Myoglobin 抗体
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北京 101111
Quick Overview for Myoglobin 抗体 (ABIN113128)
抗原
See all Myoglobin (MB) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with cardiac and skeletal forms of myoglobin.
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纯化方法
- Affinitty chromatography using immobilized human myoglobin
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纯度
- > 95 % pure
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免疫原
- Highly purified human cardiac myoglobin
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应用备注
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Immunoassays for human myoglobin
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 9.25 mg/mL (OD280nm, E1% = 13)
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缓冲液
- 10 mM sodium phosphate and 0.85 % (w/v) sodium chloride, pH 7.2, containing 0.05 % sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Myoglobin (MB)
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别名
- Myoglobin
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背景
- Myoglobin is a small heme containing protein (153 amino acid residues, molecular weight (w/o heme) 17053 Da and theoretical pI=7.29) responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.Synonyms: MB
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基因ID
- 4151
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NCBI登录号
- NP_005359
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UniProt
- P02144
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途径
- Brown Fat Cell Differentiation
抗原
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