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CX3CR1 抗体 (N-Term)

This anti-CX3CR1 antibody is a 兔 多克隆 antibody detecting CX3CR1 in WB, FACS 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN113101
发货至: 中国

Quick Overview for CX3CR1 抗体 (N-Term) (ABIN113101)

抗原

See all CX3CR1 抗体
CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

适用

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  • 40
  • 37
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  • 1
人, 小鼠, 大鼠

宿主

  • 78
  • 6
  • 5
  • 3

克隆类型

  • 80
  • 11
多克隆

标记

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  • 2
  • 2
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  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This CX3CR1 antibody is un-conjugated

应用范围

  • 54
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  • 4
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  • 3
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  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 16
    • 6
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    • 5
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    • 4
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-21, N-Term

    特异性

    The antibody recognizes CX3CR1, N-terminal V28

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse and Rat.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Peptide corresponding to amino acids 2-21 of Human CX3CR1 Remarks: The sequence differs from those of Mouse and Rat CX3CR1 by four amino acids (3, 4).
  • 应用备注

    Immunohistochemistry (2 μg/mL). Flow Cytometry. Western blot (1/500-1/2,000). Human spleen tissue lysate can be used as positive control and approx. 50 kDa band can bedetected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

    别名

    CX3CR1 / GPR13

    背景

    CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding Human, Mouse, and Rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion and has been implicated in tumor metastasis. CX3CR1 is expressed in a variety of human tissues and cell lines.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

    基因ID

    1524

    NCBI登录号

    NP_001164642

    UniProt

    P49238

    途径

    Cellular Response to Molecule of Bacterial Origin
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