CX3CR1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for CX3CR1 抗体 (N-Term) (ABIN113101)
抗原
See all CX3CR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-21, N-Term
-
特异性
- The antibody recognizes CX3CR1, N-terminal V28
-
交叉反应 (详细)
- Species reactivity (tested):Human, Mouse and Rat.
-
纯化方法
- Immunoaffinity Chromatography.
-
免疫原
- Peptide corresponding to amino acids 2-21 of Human CX3CR1 Remarks: The sequence differs from those of Mouse and Rat CX3CR1 by four amino acids (3, 4).
-
-
-
-
应用备注
-
Immunohistochemistry (2 μg/mL). Flow Cytometry. Western blot (1/500-1/2,000). Human spleen tissue lysate can be used as positive control and approx. 50 kDa band can bedetected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS with 0.02 % Sodium Azide as preservative.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
-
别名
- CX3CR1 / GPR13
-
背景
- CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding Human, Mouse, and Rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion and has been implicated in tumor metastasis. CX3CR1 is expressed in a variety of human tissues and cell lines.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28
-
基因ID
- 1524
-
NCBI登录号
- NP_001164642
-
UniProt
- P49238
-
途径
- Cellular Response to Molecule of Bacterial Origin
抗原
-