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Collagen Type V 抗体

This 兔 多克隆 antibody specifically detects Collagen Type V in EIA 和 IF. It exhibits reactivity toward 大鼠.
产品编号 ABIN113098
发货至: 中国
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Quick Overview for Collagen Type V 抗体 (ABIN113098)

抗原

See all Collagen Type V (COL5) 抗体
Collagen Type V (COL5) (Collagen, Type V (COL5))

适用

  • 25
  • 7
  • 4
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  • 2
  • 1
  • 1
大鼠

宿主

  • 15
  • 9
  • 5

克隆类型

  • 24
  • 5
多克隆

标记

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  • 5
  • 1
  • 1
This Collagen Type V antibody is un-conjugated

应用范围

  • 21
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  • 15
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  • 5
  • 3
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  • 1
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Enzyme Immunoassay (EIA), Immunofluorescence (IF)
  • 特异性

    Cross-Reactivity (% at 1:10 RIA dilution) Rat Collagen Type V 100 % Rat Collagen Types I, III < 0.1 % Rat Elastin < 0.1 %

    纯化方法

    Ion exchange chromatography (DEAE-Trisacryl).

    免疫原

    Collagen type V extracted and purified from rat skin.
  • 应用备注

    Suitable for : ELISA (dilution >1: 100-1: 200). IFA with fluorescein anti-rabbit IgG conjugate (didilution at >1: 40 on frozen rat tissuesections). Immunostaining of extra or intracellular components in light microscopy. Quantitation of Collagen Type V in biological fluids or in culture supernatants. (SP)RIA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Reconstitute with 0.5 mL deionized water.

    注意事项

    Do Not Add Sodium Azide

    注意事项

    . Avoid cycles of freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store vial at 4 °C prior to restoration. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. For extended storage mix product with glycerol to 50% and then aliquot contents and freeze at -20 °C or below.
  • 抗原

    Collagen Type V (COL5) (Collagen, Type V (COL5))

    别名

    Collagen Type V

    背景

    Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1

    基因ID

    85490

    NCBI登录号

    NP_604447

    UniProt

    Q9JI03
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