Collagen Type V 抗体
Quick Overview for Collagen Type V 抗体 (ABIN113098)
抗原
See all Collagen Type V (COL5) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Cross-Reactivity (% at 1:10 RIA dilution) Rat Collagen Type V 100 % Rat Collagen Types I, III < 0.1 % Rat Elastin < 0.1 %
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纯化方法
- Ion exchange chromatography (DEAE-Trisacryl).
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免疫原
- Collagen type V extracted and purified from rat skin.
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应用备注
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Suitable for : ELISA (dilution >1: 100-1: 200). IFA with fluorescein anti-rabbit IgG conjugate (didilution at >1: 40 on frozen rat tissuesections). Immunostaining of extra or intracellular components in light microscopy. Quantitation of Collagen Type V in biological fluids or in culture supernatants. (SP)RIA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Reconstitute with 0.5 mL deionized water.
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注意事项
- Do Not Add Sodium Azide
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注意事项
- . Avoid cycles of freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store vial at 4 °C prior to restoration. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. For extended storage mix product with glycerol to 50% and then aliquot contents and freeze at -20 °C or below.
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- Collagen Type V (COL5) (Collagen, Type V (COL5))
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别名
- Collagen Type V
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背景
- Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1
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基因ID
- 85490
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NCBI登录号
- NP_604447
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UniProt
- Q9JI03
抗原
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