CTXB 抗体
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北京 101111
Quick Overview for CTXB 抗体 (ABIN113086)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- Beta subunit of Cholera toxin.
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纯化方法
- Protein A chromatography.
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免疫原
- Purified choleragenoid.
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应用备注
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ELISA: Titer: >1: 1,000. Also suitable for conjugation purposes. Immunoprecipitates toxin in gel techniques.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 4-5 mg/mL (OD280nm, E0.1% = 1.4)
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缓冲液
- 0.01 M PBS, pH 7.2 with 0.09 % sodium azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CTXB (CtxB Gene Product (CTXB))
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别名
- Cholera Enterotoxin Subunit B
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背景
- The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
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基因ID
- 2613962
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NCBI登录号
- NP_231099
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UniProt
- P01556
抗原
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