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CTXB 抗体

This 兔 多克隆 antibody specifically detects CTXB in EIA 和 IP. It exhibits reactivity toward Vibrio cholerae.
产品编号 ABIN113086
发货至: 中国
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Quick Overview for CTXB 抗体 (ABIN113086)

抗原

CTXB (CtxB Gene Product (CTXB))

适用

  • 8
  • 1
Vibrio cholerae

宿主

  • 6
  • 2
  • 1

克隆类型

  • 6
  • 3
多克隆

标记

  • 5
  • 1
  • 1
  • 1
  • 1
This CTXB antibody is un-conjugated

应用范围

  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
  • 特异性

    Beta subunit of Cholera toxin.

    纯化方法

    Protein A chromatography.

    免疫原

    Purified choleragenoid.
  • 应用备注

    ELISA: Titer: >1: 1,000. Also suitable for conjugation purposes. Immunoprecipitates toxin in gel techniques.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    4-5 mg/mL (OD280nm, E0.1% = 1.4)

    缓冲液

    0.01 M PBS, pH 7.2 with 0.09 % sodium azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CTXB (CtxB Gene Product (CTXB))

    别名

    Cholera Enterotoxin Subunit B

    背景

    The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

    基因ID

    2613962

    NCBI登录号

    NP_231099

    UniProt

    P01556
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