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Lactoferrin 抗体

This anti-Lactoferrin antibody is a 兔 多克隆 antibody detecting Lactoferrin in EIA 和 IEP. Suitable for 人.
产品编号 ABIN113036
发货至: 中国

Quick Overview for Lactoferrin 抗体 (ABIN113036)

抗原

See all Lactoferrin (LTF) 抗体
Lactoferrin (LTF) (Lactotransferrin (LTF))

适用

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宿主

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克隆类型

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多克隆

标记

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This Lactoferrin antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA), Immunoelectrophoresis (IEP)
  • 纯化方法

    Immunoaffinity Chromatography using antigens coupled to agarose beads

    免疫原

    Lactoferrin purified from Human colostrum
  • 应用备注

    ELISA. IEP.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    2.2 mg/mL

    缓冲液

    0.01 M Sodium Phosphate, 0.21 M Sodium Chloridel, pH 7.6 with no preservatives

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    Lactoferrin (LTF) (Lactotransferrin (LTF))

    别名

    Lactotransferrin

    背景

    Lactoferrin belongs to a family of iron-binding proteins that modulate iron metabolism, hemopoiesis, and immunologic reactions, together with transferrin and melanoma tumor antigen p97. They are evolutionary products of gene duplication and all 3 are encoded by genes on 3q. Lactoferrin is an iron binding glycoprotein with an approximate molecular weight of 80 kDa. The protein has two iron binding domains each housing one Fe3+ and the synergistic CO32- ion. The crystal structure form of human lactoferrin at 2.2A resolution exhibits 5330 protein atoms, 2Fe2+, 2CO32- and 98 carbohydrate atoms. Lactoferrin is absorbed from intestine by apical side of the membrane and localized to the nuclei. Intravenous infusion of lactoferrin is protective against lethal doses of E coli and induce bacterimia by a mechanism that downregulates neutrophil TNF alfa secretion. Recombinant human lactoferrin (rhLF), expressed and extracted from rice seed, is being evaluated for use as a dietary supplement to treat iron deficiency and/or iron deficiency induced anemia. Lactoferrin has been shown to have a role in the immune system and in early development of the embryo. A specific receptor for lactoferrin binding has been implicated in the human fetal intestine. Early embryonic localisation of lactoferrin by IHC has suggested its presence in various tissues including intestinal epitheliuem, kiney, and various regions of the brain.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

    基因ID

    9606

    UniProt

    P02788

    途径

    Transition Metal Ion Homeostasis
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