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Lactoferrin 抗体 (HRP)

LTF 适用: 人 WB, IHC (p), EIA, IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN113035
发货至: 中国
  • 抗原 See all Lactoferrin (LTF) 抗体
    Lactoferrin (LTF) (Lactotransferrin (LTF))
    适用
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    宿主
    • 113
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    克隆类型
    • 160
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    多克隆
    标记
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    This Lactoferrin antibody is conjugated to HRP
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Immunoaffinity chromatography using antigens coupled to agarose beads.
    免疫原
    Lactoferrin purified from human colostrum.
    Top Product
    Discover our top product LTF Primary Antibody
  • 应用备注
    Immunohistochemistry (1: 500 - 1: 5,000) on tissue sections.1: 5,000 - 1: 100,000 for ELISA and Western blotting with chromogenic substrates and1: 10,000 - 1: 200,000 for Western blotting with ECL substrates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    Restore with 1.5 mL distilled water. Centrifuge product if it is not completely clear after standing for 1-2 hours at room temperature.
    浓度
    0.8 mg/mL (prior to lyophilization)
    缓冲液
    0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.6, containing 15 mg/mL BSA (IgG and Protease free)
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    Lactoferrin (LTF) (Lactotransferrin (LTF))
    别名
    Lactotransferrin (LTF 产品)
    别名
    LTF antibody, GIG12 antibody, HLF2 antibody, LF antibody, Lf antibody, Csp82 antibody, MMS10R antibody, Ms10r antibody, PLF antibody, TFEW antibody, conalbumin antibody, lactotransferrin antibody, transferrin antibody, transferrin (ovotransferrin) antibody, LTF antibody, CpipJ_CPIJ000114 antibody, TF antibody, Ltf antibody
    背景
    Lactoferrin belongs to a family of iron-binding proteins that modulate iron metabolism, hemopoiesis, and immunologic reactions, together with transferrin and melanoma tumor antigen p97. They are evolutionary products of gene duplication and all 3 are encoded by genes on 3q. Lactoferrin is an iron binding glycoprotein with an approximate molecular weight of 80 kDa. The protein has two iron binding domains each housing one Fe3+ and the synergistic CO32- ion. The crystal structure form of human lactoferrin at 2.2A resolution exhibits 5330 protein atoms, 2Fe2+, 2CO32- and 98 carbohydrate atoms. Lactoferrin is absorbed from intestine by apical side of the membrane and localized to the nuclei. Intravenous infusion of lactoferrin is protective against lethal doses of E coli and induce bacterimia by a mechanism that downregulates neutrophil TNF alfa secretion. Recombinant human lactoferrin (rhLF), expressed and extracted from rice seed, is being evaluated for use as a dietary supplement to treat iron deficiency and/or iron deficiency induced anemia. Lactoferrin has been shown to have a role in the immune system and in early development of the embryo. A specific receptor for lactoferrin binding has been implicated in the human fetal intestine. Early embryonic localisation of lactoferrin by IHC has suggested its presence in various tissues including intestinal epitheliuem, kiney, and various regions of the brain.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin
    基因ID
    9606
    UniProt
    P02788
    途径
    Transition Metal Ion Homeostasis
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