Shows only the SSA precipitate band when tested using double immunodiffusion against bovine spleen extract. Specificity is verified by identity of precipitation with CDC-AF reference serum. Titer will vary with test system, however, undiluted antibody shows a strong SSA precipitate band. Exhibits no reactivity at a dilution of 1:100 when tested against purified SSB, Scl-70, Sm, Sm/RNP, and Jo-1 antigens in an ELISA system designed to detect all IgG subclasses.
纯化方法
The human plasma is delipidized and defibrinated, then the immunoglobulin fraction is precipitated and collected.