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Vasopressin 抗体

This anti-Vasopressin antibody is a 兔 多克隆 antibody detecting Vasopressin in IF, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN112917
发货至: 中国

Quick Overview for Vasopressin 抗体 (ABIN112917)

抗原

See all Vasopressin (AVP) 抗体
Vasopressin (AVP) (Arginine Vasopressin (AVP))

适用

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宿主

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克隆类型

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多克隆

标记

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This Vasopressin antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 特异性

    This antibody is specific for Arginine Vasopressin, also known as antidiuretic hormone. The sequence of ARG-Vasopressin is 100 % identical in a vast number of species such as Human, Mouse, Rat, Cat, Dog, Bovine, Sheep, Guinea Pig, so a broad species. crossreactivity is to be expected.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Synthetic Arginine Vasopressin conjugated to Bovine thyroglobulin
  • 应用备注

    Immunohistochemistry on Frozen and Paraffin Embedded Tissues. Immunofluorescence. Histology Positive Control Tissue: Hypothalamus and posterior lobe of the pituitary gland.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    5.0 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Vasopressin (AVP) (Arginine Vasopressin (AVP))

    别名

    Vasopressin-Neurophysin 2-Copeptin

    背景

    Vasopressin, also known as arginine vasopressin (AVP), or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria. Arginine vasopressin is a nine amino acid peptide secreted from the posterior pituitary in response to reductions in plasma volume and increases is plasma osmolarity. Its release triggers water reabsorption due to the insertion of aquaporins in the membranes of kidney tubules which transport solute-free water through tubular cells and back into the blood.Synonyms: ARVP, AVP, Antidiuretic Hormone, Arginine vasopressin

    基因ID

    551

    NCBI登录号

    NP_000481

    UniProt

    P01185

    途径

    cAMP Metabolic Process
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