ENO1 抗体
Our Local Distributor
北京 101111
Quick Overview for ENO1 抗体 (ABIN112663)
抗原
See all ENO1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects Human Non-Neuronal Enolase, and demostrates less than 0.1 % cross-reactivity with non-specific Enolase.
-
纯化方法
- Affinity Chromatography on Protein G
-
免疫原
- Native Human NNE.
-
-
-
-
应用备注
-
Immunohistochemistry on Frozen and Paraffin Sections (each 1/25-1/100). ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 5.0 mg/mL (by OD 280 nm)
-
缓冲液
- PBS, 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- ENO1 (Enolase 1 (ENO1))
-
别名
- alpha-Enolase (ENO1)
-
背景
- Non Neuronal Enolase (ENO1) is an isoform of mammalian enolase and is composed of 2 alpha subunits. The gene for ENO1 encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. Non Neuronal Enolase can be as a diagnostic marker for many tumors, as a marker for endometriosis and in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. It has been identified as an autoantigen in Hashimoto encephalopathy (associated with Hashimoto thyroiditis).Synonyms: 2-phospho-D-glycerate hydro-lyase, C-myc promoter-binding protein, ENO1L1 Non-neural enolase, Enolase 1, MBP-1, MBPB1, MPB-1, MPB1, NNE, Phosphopyruvate hydratase, Plasminogen-binding protein
-
基因ID
- 2023
-
NCBI登录号
- NP_001188412
-
UniProt
- P06733
抗原
-