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Inhibin alpha 抗体 (N-Term)

This anti-Inhibin alpha antibody is a 兔 多克隆 antibody detecting Inhibin alpha in IHC (p), IHC (fro) 和 EIA. Suitable for 人.
产品编号 ABIN112650
发货至: 中国

Quick Overview for Inhibin alpha 抗体 (N-Term) (ABIN112650)

抗原

See all Inhibin alpha (INHA) 抗体
Inhibin alpha (INHA) (Inhibin, alpha (INHA))

适用

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宿主

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克隆类型

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多克隆

标记

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This Inhibin alpha antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
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    AA 1-24, N-Term

    序列

    S-T-P-L-M-S-W-P-W-S-P-S-A-L-R-L-L-Q-R-P-P-E-E-P-G-Y

    特异性

    This antibody recognizes Inhibin alpha, which is expressed in a range of tissues including prostate, brain, adrenal gland, testis and ovary.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Synthetic peptide corresponding to the amino acids 1-24 of Human Inhibin alpha

    亚型

    IgG
  • 应用备注

    ELISA. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: 1/400. This antibody stains primordial follicles when using paraffin embedded, formalin fixedfragments of human ovarian cortex.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    5.0 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Inhibin alpha (INHA) (Inhibin, alpha (INHA))

    别名

    Inhibin alpha / INHA

    背景

    Inhibins are peptide hormones produced by the granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules. They are selectively expressed by cells of sex cord stromal derivation, and inhibit the secretion of follitropin by the pituitary gland. Inhibins are also involved in regulating diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins, as inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibin has 2 subunits (alpha and beta) that are coded by separate genes. The alpha subunit determines whether inhibin or activin will be produced. The alpha subunit remains constant, such that the various types of inhibin are defined by the beta subunit (a,b,c,d). Inhibin A is a dimer of alpha and beta A. Inhibin B is a dimer of alpha and beta B. Proteolytic processing yields a number of inhibin alpha bioactive forms: the 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N terminal propeptide linked through a disulfide bond to the mature alpha chain, and the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono or diglycosylated, causing the mass difference.

    基因ID

    3623

    NCBI登录号

    NP_002182

    UniProt

    P05111

    途径

    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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