This antibody is specific for an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.
纯化方法
Affinity Chromatography on Protein G.
免疫原
Denatured Tissue factor isolated from human brain by the Factor VII affinity method.
ELISA. Western blot. Flow Cytometry. Immunofluorescence. Immunohistology on Frozen and Paraffin Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
Phosphate buffered saline containing 0.09 % Sodium Azide as preservative and 200 mM Mannitol as stabilizer.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
Tissue factor (F3)
(Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
CD142, also known as Tissue factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation.Synonyms: Coagulation factor III, F3, TF, Thromboplastin