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Thyroglobulin 抗体

TG 适用: 人 IHC (p), EIA, ELISA (Detection) 宿主: 小鼠 Monoclonal BGN-6D7 (5E6) unconjugated
产品编号 ABIN112489
发货至: 中国
  • 抗原 See all Thyroglobulin (TG) 抗体
    Thyroglobulin (TG)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Thyroglobulin antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), ELISA (Detection)
    特异性
    This antibody recognizes Thyroglobulin (Tg), reacting with circulating Tg (Tg/T4 complex). Reacts with a different epitope to clone BGN/6E10 (AM01234PU-N) and can be used as the conjugated antibody in 2 site assay with this clone.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Purified Human Thyroglobulin.
    克隆位点
    BGN-6D7 (5E6)
    亚型
    IgG2b
    Top Product
    Discover our top product TG Primary Antibody
  • 应用备注
    ELISA: This antibody is suitable for use as a detection antibody in a sandwich ELISA usingABIN180965 as the Capture antibody. Immunohistochemistry on Paraffin Sections: 10 μg/mL. This Thyroglobulin antibody was validated for use in immunohistochemistry on a panel of21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Thyroglobulin (TG)
    Abstract
    TG 产品
    别名
    TG antibody, cb717 antibody, AITD3 antibody, TGN antibody, Tgn antibody, cog antibody, thyroglobulin antibody, TG antibody, tg antibody, LOC701526 antibody, LOC701756 antibody, LOC100434297 antibody, Tg antibody
    背景
    Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.Synonyms: TGN, Thyreoglobulin
    基因ID
    7038
    NCBI登录号
    NP_003226
    UniProt
    P01266
    途径
    Thyroid Hormone Synthesis
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