Thyroglobulin 抗体
Quick Overview for Thyroglobulin 抗体 (ABIN112489)
抗原
See all Thyroglobulin (TG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes Thyroglobulin (Tg), reacting with circulating Tg (Tg/T4 complex). Reacts with a different epitope to clone BGN/6E10 (AM01234PU-N) and can be used as the conjugated antibody in 2 site assay with this clone.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Purified Human Thyroglobulin.
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亚型
- IgG2b
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anti-Thyroglobulin (TG) (AA 2659-2768) antibody
TG 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal r6E1 unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal r2H11 unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-189R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) (AA 2083-2333) antibodyTG 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人, Cow IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, StM 宿主: 兔 Monoclonal TGB-1970R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) (C-Term) antibodyTG 适用: 人 IHC (p) 宿主: 兔 Monoclonal E23-Y unconjugated
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应用备注
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ELISA: This antibody is suitable for use as a detection antibody in a sandwich ELISA usingABIN180965 as the Capture antibody. Immunohistochemistry on Paraffin Sections: 10 μg/mL. This Thyroglobulin antibody was validated for use in immunohistochemistry on a panel of21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Thyroglobulin (TG)
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背景
- Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.Synonyms: TGN, Thyreoglobulin
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基因ID
- 7038
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NCBI登录号
- NP_003226
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UniProt
- P01266
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途径
- Thyroid Hormone Synthesis
抗原
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