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beta-2 Microglobulin 抗体 (Biotin)

Cited in 3+ publications. The Biotin-conjugated 小鼠 单克隆 anti-beta-2 Microglobulin antibody (Clone B2M-01) (ABIN112398) specifically detects beta-2 Microglobulin in WB, FACS, IP, IHC (p), RIA 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN112398
发货至: 中国
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Quick Overview for beta-2 Microglobulin 抗体 (Biotin) (ABIN112398)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This beta-2 Microglobulin antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

克隆位点

B2M-01
  • 特异性

    The antibody reacts with Beta-2-microglobulin (b2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble Beta-2-microglobulin.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    免疫原

    Purified Human Beta-2-microglobulin

    亚型

    IgG2a
  • 应用备注

    Flow cytometry (1/200).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Poláková, Železníková, Russ: "HLA-G5 in the blood of leukemia patients and healthy individuals." in: Leukemia research, Vol. 37, Issue 2, pp. 139-45, (2013) (PubMed).

    Khurana, Traum, Aivado, Wells, Guerrero, Grall, Libermann, Schachter: "Urine proteomic profiling of pediatric nephrotic syndrome." in: Pediatric nephrology (Berlin, Germany), Vol. 21, Issue 9, pp. 1257-65, (2006) (PubMed).

    Lafon, Prehaud, Megret, Lafage, Mouillot, Roa, Moreau, Rouas-Freiss, Carosella: "Modulation of HLA-G expression in human neural cells after neurotropic viral infections." in: Journal of virology, Vol. 79, Issue 24, pp. 15226-37, (2005) (PubMed).

  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    beta-2-Microglobulin

    背景

    B2M is a 12 kDa Ig like glycoprotein. It non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin

    基因ID

    567

    NCBI登录号

    NP_004039

    UniProt

    P61769

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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