Reticulon 1 抗体
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- 抗原 See all Reticulon 1 (RTN1) 抗体
- Reticulon 1 (RTN1)
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适用
- 人, 兔, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Reticulon 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- RNL-2 recognizes an epitope located within the region of amino acids 421-589 of the neuroendocrine specific protein Reticulon-1A (NSP-A), which is also present in the N-terminal part of Reticulon-1B (NSP-B). In normal tissues, RNL-2 reacts with brain Purkinje cells, pancreatic islet cells, cells in the pituitary gland and some (peripheral) nerve fibers. In addition, a few epithelia show positive staining.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Rabbit and Rhesus Monkey.
- 纯化方法
- Purified
- 免疫原
- The small cell lung cancer cell line NCI-H82.
- 克隆位点
- RNL-2
- 亚型
- IgG1
- Top Product
- Discover our top product RTN1 Primary Antibody
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anti-Reticulon 1 (RTN1) (AA 338-422) antibody
RTN1 适用: 人, 小鼠, 大鼠, Hamster WB, IHC (fro), IHC, ICC 宿主: 小鼠 Monoclonal MON162 unconjugated
anti-Reticulon 1 (RTN1) antibodyRTN1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 1 (RTN1) (AA 36-85) antibodyRTN1 适用: 人, 小鼠, 大鼠, 猴, Cow, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 1 (RTN1) (C-Term) antibodyRTN1 适用: 人, 小鼠, 大鼠, 兔, 猴, Pig, 犬, 豚鼠, 斑马鱼, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 1 (RTN1) antibodyRTN1 适用: 人, 大鼠, Pig WB, IHC (fro), IHC, ICC, FACS 宿主: 小鼠 Monoclonal RNL-4 unconjugated
anti-Reticulon 1 (RTN1) (AA 421-589) antibodyRTN1 适用: 人, 兔, 猴 WB, IHC (fro), IHC, ICC, FACS, IHC (p) 宿主: 小鼠 Monoclonal RNL-2 unconjugated
anti-Reticulon 1 (RTN1) (AA 80-340) antibodyRTN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 1 (RTN1) (AA 589-776) antibodyRTN1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 1 (RTN1) (AA 593-780) antibodyRTN1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Reticulon 1 (RTN1) (AA 198-227), (N-Term) antibodyRTN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36663 unconjugated
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- 应用备注
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Suitable for Immunocytochemistry, Immunohistochemistry on frozen tissues,Immunoblotting and Flow cytometry. Recommended dilutions: 1/25-1/200 for Flow cytometry, and for Immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent.1/100-1/1000 for Immunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted -20 °C only.
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- 抗原
- Reticulon 1 (RTN1)
- 别名
- Reticulon 1 / RTN1 (RTN1 产品)
- 别名
- NSP antibody, 0710005K15Rik antibody, 4930441F12Rik antibody, Nsp antibody, R75279 antibody, Rtn1-a antibody, Rtn1-b antibody, Rtn1-c antibody, reticulon-1 antibody, RTN1 antibody, RTN1-Cw antibody, rtn1 antibody, XRTN1-A antibody, XRTN1-C.1 antibody, xrtn1 antibody, xrtn1-c antibody, RTN1.2 antibody, Rtn1-C.2 antibody, rtn1-a antibody, rtn1b antibody, xRTN1 antibody, RTN1.1 antibody, rtn1a antibody, xrtn1-c.1 antibody, rtn1l antibody, wu:fa21b09 antibody, wu:fj35h01 antibody, reticulon 1 antibody, reticulon-1 antibody, reticulon 1 S homeolog antibody, reticulon 1 L homeolog antibody, reticulon 1b antibody, RTN1 antibody, Rtn1 antibody, rtn1 antibody, Rtnl1 antibody, LOC100580843 antibody, rtn1.S antibody, rtn1.L antibody, LOC100339591 antibody, rtn1b antibody
- 背景
- Recently, a novel gene family has been identified and characterized, designated the Reticulons because the proteins encoded by these genes are anchored to the membranes of the endoplasmic reticulum. Reticulon-1 was formerly designated NSP for Neuroendocrine-Specific-Protein, because it is specifically expressed in neural and neuroendocrine tissues. The NSP-gene has been mapped by fluorescence in situ hybridization to human chromosome 14q21-q22. The NSP-gene encodes three overlapping proteins, i.e. Reticulon-1A (NSPA), Reticulon-1B (NSP-B), and Reticulon-1C (NSPC). These proteins were found to be anchored to membranes of the endoplasmic reticulum through their common carboxy-terminal regions. Reticulon-1A is a protein with a molecular weight (MW) of about 135 kDa, which occurs in various isoforms presumably depending on the degree of phosphorylation of serine residues. In lung cancer diagnosis Reticulon-1A appeared to be a reliable marker for the detection of neuroendocrine differentiation, since most of the small cell lung carcinoma (SCLC) and carcinoid tumors showed expression of Reticulon-1A. Reticulon-1B is a phosphoprotein with a MW of 45 kDa and is restricted to the lung cancer cell line NCI-H82. Reticulon-1B is sofar not found in human tissues. Reticulon-1C is a protein with a MW of 23 kDa which is not phosphorylated and is found with Reticulon-1A in SCLC (cell lines) and not in non-SCLC (cell cultures).Synonyms: NSP, Neuroendocrine-specific protein, RTN1, Reticulon-1
- 基因ID
- 6252
- NCBI登录号
- NP_066959
- UniProt
- Q16799
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