Selectin E/CD62e 抗体
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- 抗原 See all Selectin E/CD62e (SELE) 抗体
- Selectin E/CD62e (SELE) (Selectin E (SELE))
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适用
- 人, 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Selectin E/CD62e antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- Purified
- 免疫原
- LPS-activated mlEND1 cells expressing E-selectin at their cell surface
- 克隆位点
- UZ4
- 亚型
- IgM
- Top Product
- Discover our top product SELE Primary Antibody
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anti-Selectin E (SELE) (AA 501-612) antibody
SELE 适用: 人, Pig, 小鼠, 大鼠 WB, ELISA, FACS, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 22-230) antibodySELE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (N-Term) antibodySELE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 108-238) antibodySELE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) (AA 260-420) antibodySELE 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 小鼠 WB, IHC, ELISA, FACS, IP, IHC (fro), ICC, Func 宿主: 大鼠 Monoclonal UZ5 unconjugated
anti-Selectin E (SELE) antibodySELE 适用: 人 ELISA 宿主: 小鼠 Monoclonal B-P7 unconjugated
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- 应用备注
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UZ4 is a functional antibody in that it inhibits leukocyte adhesion to both murine andhuman activated endothelial cells. For in vivo application in mice 20 g of purified Ig perinjection is recommended. UZ4 is also suitable for immunoblotting, ELISA, immunoprecipitation and flow cytometry(dilution 1: 500). It is not optimal for immunohistochemistry, to analyze mouse E-selectin protein in frozensections, please refer to the anti E-selectin monoclonal antibodies UZ5 (ABIN112380), UZ6(ABIN112381), and UZ7 (ABIN112382).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- 别名
- CD62E / E-Selectin (SELE 产品)
- 别名
- SELE antibody, CD62E antibody, ELAM antibody, ELAM1 antibody, ESEL antibody, LECAM2 antibody, E-selectin antibody, Elam antibody, selectin E antibody, selectin, endothelial cell antibody, SELE antibody, Sele antibody
- 背景
- Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes. In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation. This response is immediate and involves a cascade of adhesion receptors. At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade. Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium. E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines. In vitro experiments have shown that IL-1, TNF-alpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signalling cascade. E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.Synonyms: CD62 antigen-like family member E, ELAM1, Endothelial leukocyte adhesion molecule 1, LECAM2, Leukocyte-endothelial cell adhesion molecule 2, SELE
- 基因ID
- 9606
- UniProt
- P16581
- 途径
- Thromboxane A2 Receptor Signaling
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