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ITGB1 抗体 (C-Term, N-Term)

The 小鼠 单克隆 anti-ITGB1 antibody (Clone 2B1) (ABIN112374) specifically detects ITGB1 in WB, IF 和 IHC (fro). The antibody is reactive with 人, 小鼠, Pig 和 犬 samples.
产品编号 ABIN112374
发货至: 中国
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Quick Overview for ITGB1 抗体 (C-Term, N-Term) (ABIN112374)

抗原

See all ITGB1 抗体
ITGB1 (Integrin beta 1 (ITGB1))

适用

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人, 小鼠, Pig, 犬

宿主

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  • 100
  • 13
  • 12
  • 1
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  • 1
小鼠

克隆类型

  • 173
  • 138
  • 1
单克隆

标记

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This ITGB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

2B1
  • 抗原表位

    • 16
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    • 11
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    C-Term, N-Term

    序列

    CQENPIYKS-PINNFKNPNY GRKAGL

    纯化方法

    Purified

    免疫原

    A synthetic peptide corresponding to the C-terminal 24 amino acids of integrin b1D including an appending N-terminal cysteine coupled to keyhole limpet hemocyanin.

    亚型

    IgG1
  • 应用备注

    Immunoblotting: 1: 100 - 1: 1000. Immunocytochemistry. Immunohistochemistry on frozen tissue: 1/25 -1/200 with an ABC method.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.09 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store undiluted (in aliquots) at -20 °C.
  • 抗原

    ITGB1 (Integrin beta 1 (ITGB1))

    别名

    CD29 / Integrin beta-1

    背景

    Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. Their distribution pattern in adult tissues is mutually exclusive. bea1A is present in all tissues, except cardiac and skeletal muscle, which instead express the beta1D variant.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

    基因ID

    9606

    UniProt

    P05556

    途径

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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