ITGA6 抗体 (Isoform 6B, N-Term)
Quick Overview for ITGA6 抗体 (Isoform 6B, N-Term) (ABIN112373)
抗原
See all ITGA6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Isoform 6B, N-Term
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序列
- CSRYDDSVPR YHAVRIRKEE REIKDEKYID NLEKK
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特异性
- It recognizes specifically the cytoplasmic domain of integrin subunit alpha-6B. 6B4 stains the basement membrane zone of ducts and acini of salivary gland, kidney tubules, epithelium of colonic crypts and weakly stains sweat glands and sebaceous glands. A broad species reactivity is expected because of the conserved nature of the epitope.
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纯化方法
- Purified
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免疫原
- 6B4 is a mouse monoclonal IgG1, k antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a synthetic peptide corresponding to a 34 amino acid stretch in the cytoplasmic domain of integrin a6B including an appending N-terminal Cysteine coupled to keyhole limpet hemocyanin.
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亚型
- IgG1
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anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibody
ITGA6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人 FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 129CT49-6-5 unconjugated
anti-Integrin, alpha 6 (ITGA6) (Ser1064) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1082-1110), (C-Term) antibodyITGA6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18006 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1043-1072), (Isoform 2) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15309 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 625-866) antibodyITGA6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibody (APC)ITGA6 适用: 人, 小鼠, 犬, Cow, Pig, 绵羊, 马, 兔, Cat, Non-Human Primate FACS 宿主: 大鼠 Monoclonal GoH3 APC
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人, 小鼠, 犬, Pig, 绵羊, Cynomolgus FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal NKI-GoH3 unconjugated
anti-Integrin, alpha 6 (ITGA6) antibody (PE)ITGA6 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal Mab-5A PE
anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibodyITGA6 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 马, Hamster, 豚鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Suitable for Immunoblotting, Immunocytochemistry, Immunohistochemistry on frozensections. Recommended dilutions: 1/50-1/100 for Flow cytometry, and for Immunohistochemistrywith avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and1/100-1/500 for Immunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the lyophilized antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. When reconstituted the antibody is stable for one month at 2-8 °C.
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- ITGA6 (Integrin, alpha 6 (ITGA6))
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别名
- CD49f / ITGA6
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背景
- Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated a and b subunits. More than 18 a and 8 b subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits a3 and a6, two cytoplasmic variants, A and B, have been identified.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
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基因ID
- 3655
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NCBI登录号
- NP_000201
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UniProt
- P23229
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途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
抗原
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