ITGA3 抗体 (Isoform 3B, N-Term)
Our Local Distributor
北京 101111
Quick Overview for ITGA3 抗体 (Isoform 3B, N-Term) (ABIN112371)
抗原
See all ITGA3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- Isoform 3B, N-Term
-
序列
- CTRYYQIMPK YHAVRIREEE RYPPPGSTLP TKK
-
特异性
- 54B3 recognizes specifically the cytoplasmic domain of integrin subunit a3B which is present in microvascular structures in brain and heart.
-
纯化方法
- Purified
-
免疫原
- Synthetic peptide corresponding to a 32 amino acid stretch in the cytoplasmic domain of integrin alpha3B including an appending N-terminal cysteine coupled to keyhole limpet hemocyanin.
-
亚型
- IgG1
-
-
-
-
应用备注
-
Immunoblotting (1: 100 - 1: 1000). Immunocytochemistry. Immunohistochemistry on frozen tissues (1: 25 - 1: 200, with avidin-biotinylated horseradishperoxidase complex (ABC) as detection reagent).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- ITGA3 (Integrin, alpha 3 (ITGA3))
-
别名
- CD49c / ITGA3
-
背景
- Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated α and β subunits. More than 18 α and 8 β subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits α3 and α6, two cytoplasmic variants, A and B, have been identified.Synonyms: CD49 antigen-like family member C, FRP-2, GAPB3, Galactoprotein B3, ITGA-3, ITGAG3, Integrin alpha-3, MSK18, VLA-3 alpha chain, VLA3
-
基因ID
- 3675
-
NCBI登录号
- NP_002195
-
UniProt
- P26006
-
途径
- CXCR4-mediated Signaling Events, Integrin Complex
抗原
-