电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ITGA3 抗体 (Isoform 3A, N-Term)

This anti-ITGA3 antibody is a 小鼠 单克隆 antibody detecting ITGA3 in WB, IF 和 IHC (fro). Suitable for 人 和 犬.
产品编号 ABIN112369
发货至: 中国

Quick Overview for ITGA3 抗体 (Isoform 3A, N-Term) (ABIN112369)

抗原

See all ITGA3 抗体
ITGA3 (Integrin, alpha 3 (ITGA3))

适用

  • 53
  • 37
  • 17
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
人, 犬

宿主

  • 51
  • 17
  • 3
  • 1
小鼠

克隆类型

  • 55
  • 19
单克隆

标记

  • 39
  • 6
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ITGA3 antibody is un-conjugated

应用范围

  • 46
  • 35
  • 24
  • 16
  • 10
  • 9
  • 9
  • 8
  • 6
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

158A3
  • 抗原表位

    • 16
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform 3A, N-Term

    特异性

    This antibody Clone 158A3 reacts exclusively with the cytoplasmic domain of non-phosphorylated Integrin subunit α3A. A broad species reactivity is expected because of the conserved nature of the epitope.

    纯化方法

    Purified

    免疫原

    158A3 is a mouse monoclonal IgG2a antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a synthetic peptide corresponding to the cytoplasmic domain of the integrin subunit a3A including an additional N-terminal cysteine (CRTRALYEAKRQKAEMKSQPSETERLTDDY) coupled to keyhole limpet hemocyanin.

    亚型

    IgG2a
  • 应用备注

    158A3 is suitable for Immunoblotting, Immunocytochemistry, Immunohistochemistry onfrozen sections. Recommended dilutions: 1/100-1/200 for Immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent, and 1/100-1/1000 forImmunoblotting applications.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at -20 °C.
  • 抗原

    ITGA3 (Integrin, alpha 3 (ITGA3))

    别名

    CD49c / ITGA3

    背景

    Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated a and b subunits. More than 18 a and 8 b subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits a3 and a6, two cytoplasmic variants, A and B, have been identified.Synonyms: CD49 antigen-like family member C, FRP-2, GAPB3, Galactoprotein B3, ITGA-3, ITGAG3, Integrin alpha-3, MSK18, VLA-3 alpha chain, VLA3

    基因ID

    3675

    NCBI登录号

    NP_002195

    UniProt

    P26006

    途径

    CXCR4-mediated Signaling Events, Integrin Complex
You are here:
Chat with us!