OB Cadherin 抗体 (Extracellular Domain)
Quick Overview for OB Cadherin 抗体 (Extracellular Domain) (ABIN112366)
抗原
See all OB Cadherin (CDH11) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody recognizes the extracellular domain of Cadherin-11.
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纯化方法
- Affinity Chromatography
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免疫原
- 16A is a mouse monoclonal IgG1 antibody obtained by fusion of SP2/0 Mouse myeloma cells with spleen cells from a Mouse immunized with affinity purified extracellular domain of Human Cadherin-11-GST fusion protein.
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亚型
- IgG1
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anti-Cadherin 11 (CDH11) (AA 54-612) antibody
CDH11 适用: 人 WB, ELISA, IP, FACS, Func 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Cadherin 11 (CDH11) (AA 468-617) antibodyCDH11 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2C12A6 unconjugated
anti-Cadherin 11 (CDH11) (AA 468-617) antibodyCDH11 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4E12G10 unconjugated
anti-Cadherin 11 (CDH11) (AA 54-612) antibodyCDH11 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Cadherin 11 (CDH11) (AA 637-796) antibodyCDH11 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) (AA 310-360) antibodyCDH11 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) antibodyCDH11 适用: 人, 大鼠 WB, IHC, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 16A unconjugated
anti-Cadherin 11 (CDH11) (AA 509-617) antibodyCDH11 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Cadherin 11 (CDH11) (Internal Region) antibodyCDH11 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) (AA 374-595) antibodyCDH11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suitable for Immunoblotting, Immunocytochemistry and Immunohistochemistry on Frozensections when using a PBS buffer containing 0.1 mM CaCl2 and 0.1 mM MgCl2. Recommended Dilutions: 1/25-1/50 for Immunohistochemistry with Avidin-biotinylatedHorseradish Peroxidase Complex (ABC) as detection reagent.1/25-1/250 for Immunoblotting applications.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the original vial at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
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别名
- Cadherin-11
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背景
- Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. The cadherins generally contain five extracellular repeats, a transmembrane domain and a cytoplasmic tail that binds to the catenin family of cytoskeletal anchoring proteins which also function as signal transducers. The extracellular domains are responsible for the specificity of homophilic interactions between cells expressing the same cadherin. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4). Kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. The progression of carcinomas is associated with the loss of epithelial morphology and a concomitant acquisition of a more mesenchymal phenotype, which is thought to contribute to the invasive and/or metastatic behavior. A putative role for cadherin-11 in these late stages of tumor progression is based on the fact that migration of mesenchymal cells is facilitated when cadherin-11 is highly expressed.Synonyms: CDH11, OB Cadherin, OSF-4, Osteoblast cadherin
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基因ID
- 1009
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NCBI登录号
- NP_001788
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UniProt
- P55287
抗原
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