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KRT4 抗体

KRT4 适用: 人, 犬, Cat, 斑马鱼 WB, FACS, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 6B10 unconjugated
产品编号 ABIN112320
发货至: 中国
  • 抗原 See all KRT4 抗体
    KRT4 (Keratin 4 (KRT4))
    适用
    • 70
    • 39
    • 18
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    人, 犬, Cat, 斑马鱼
    宿主
    • 63
    • 14
    • 1
    小鼠
    克隆类型
    • 53
    • 25
    单克隆
    标记
    • 35
    • 9
    • 5
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
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    This KRT4 antibody is un-conjugated
    应用范围
    • 51
    • 23
    • 18
    • 15
    • 14
    • 13
    • 12
    • 9
    • 7
    • 5
    • 4
    • 1
    • 1
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    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This Monoclonal antibody 6B10 reacts exlcusively with Cytokeratin 4 which is present in non-cornifying squamous epithelium, including cornea and transitional epithelium. Cells in certain ciliated pseudo-stratified epithelia and ductal epithelia of various exocrine glands are also positive for 6B10.
    交叉反应 (详细)
    Species reactivity (tested):Human, Canine, Feline, Zebrafish.
    纯化方法
    Purified
    免疫原
    6B10 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a cytokeratin preparation extracted from human esophagus.
    克隆位点
    6B10
    亚型
    IgG1
    Top Product
    Discover our top product KRT4 Primary Antibody
  • 应用备注
    Immunocytochemistry. Immunohistochemistry on Frozen and Tissues (1/25-1/200) using with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent. Immunoblotting (1/100-1/1000). Flow Cytometry (1/25-1/200).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Liu, Li, Tan, Beuerman: "The eyelid margin: a transitional zone for 2 epithelial phenotypes." in: Archives of ophthalmology (Chicago, Ill. : 1960), Vol. 125, Issue 4, pp. 523-32, (2007) (PubMed).

  • 抗原
    KRT4 (Keratin 4 (KRT4))
    别名
    Cytokeratin 4 (KRT4 产品)
    别名
    cb59 antibody, etID20321.6 antibody, krt8 antibody, wu:fa91a11 antibody, wu:fd19e09 antibody, wu:fl23c09 antibody, zf-K8 antibody, CK-4 antibody, CK4 antibody, CYK4 antibody, K4 antibody, Kb4 antibody, AW108092 antibody, Krt-2.4 antibody, Krt2-4 antibody, keratin 4 antibody, krt4 antibody, KRT4 antibody, Krt4 antibody
    背景
    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK4, CYK4, Cytokeratin-4, K4, KRT4, Keratin, Keratin-4, type II cytoskeletal 4
    基因ID
    9606
    UniProt
    P19013
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