LRPAP1 抗体
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北京 101111
Quick Overview for LRPAP1 抗体 (ABIN112189)
抗原
See all LRPAP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody BM5054 (7F1) reacts with the 39 kDa RAP protein, which is cosynthesized with Human LRP/alpha2MR (low density lipoprotein receptor-related protein/alpha2-Macro-Globulin Receptor). It inhibits the binding of ligands, e.g. tPA, uPA, VLDL, liproprotein lipase, and alpha2-Macroglobulin-proteinase complexes to LRP/A2MR.
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纯化方法
- Affinity Chromatography on Protein A .
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免疫原
- Human RAP.
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亚型
- IgG1
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应用备注
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Immunoblotting. Immunofluorescence. Immunohistochemistry: 1/20. Ligand-binding assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in 1 mL distilled water.
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缓冲液
- PBS buffer, pH 7.4 containing 0.5 % BSA as stabilizer.
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注意事项
- This product is photosensitive and should be protected from light
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储存条件
- 4 °C
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储存方法
- Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))
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别名
- LRPAP1 / A2MRAP
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背景
- Low density lipoprotein receptor-related protein-associated protein 1 (RAP) interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. It is present on the cell surface forming a complex with the alpha 2 macroglobulin receptor heavy and light chains. Binds LRP1B, binding is followed by internalization and degradation. In complex with the alpha 2 MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.Synonyms: Alpha-2-MRAP, Alpha-2-macroglobulin receptor-associated protein, Low density lipoprotein receptor-related protein-associated protein 1, RAP
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基因ID
- 4043
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NCBI登录号
- NP_002328
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UniProt
- P30533
抗原
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