GFAP 抗体
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北京 101111
Quick Overview for GFAP 抗体 (ABIN112031)
抗原
See all GFAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes GFAP. It may react with GFAP from other species.
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交叉反应 (详细)
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Species reactivity (expected):Macaque.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Native
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亚型
- IgG1
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应用备注
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ELISA (has been used with antigen coated at 5 μg/mL, endpoint titer of a 1 mg/mL solutionof this antibody is around 1/500,000). Western blot (recognizes 38-45 kDa neurofilaments). Immunohistochemistry on Frozen Sections and cell smears (0.1-10 μg per slide may beused as a guide). Immunflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Systemic neurochemical alterations in schizophrenic brain: glutamate metabolism in focus." in: Neurochemical research, Vol. 32, Issue 9, pp. 1434-44, (2007) (PubMed).
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- GFAP (Glial Fibrillary Acidic Protein (GFAP))
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别名
- GFAP
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背景
- Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.Synonyms: Glial Fibrillary Acidic Protein
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基因ID
- 2670
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NCBI登录号
- NP_001229305
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UniProt
- P14136
抗原
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