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AIMP1 抗体

AIMP1 适用: 人, 大鼠 WB, EIA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 546-2 unconjugated
产品编号 ABIN112011
发货至: 中国
  • 抗原 See all AIMP1 抗体
    AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
    适用
    • 57
    • 17
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 46
    • 7
    • 5
    小鼠
    克隆类型
    • 51
    • 7
    单克隆
    标记
    • 30
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIMP1 antibody is un-conjugated
    应用范围
    • 45
    • 20
    • 13
    • 13
    • 10
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody reacts with Endothelial-Monocyte-Activating Polypeptide II (EMAP II).
    交叉反应 (详细)
    Species reactivity (tested):Human, Rat.
    纯化方法
    Affinity Chromatography.
    免疫原
    Recombinant Human EMAPII. The epitope has not been further characterized.
    克隆位点
    546-2
    亚型
    IgG
    Top Product
    Discover our top product AIMP1 Primary Antibody
  • 应用备注
    Immunohistochemistry on Frozen Sections: 10 μg/mL (1/40)Immunohistochemistry on Paraffin Sections: 10 μg/mL (1/40). Microwave pretreatment forantigen retrieval is recommended. Recommended Positive Control: Rat spleen. Has been described to work in ELISA and Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Reconstitute by adding 0.5 mL distilled water.
    浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
    别名
    SCYE1 / EMAP2 (AIMP1 产品)
    别名
    EMAP2 antibody, EMAPII antibody, HLD3 antibody, SCYE1 antibody, p43 antibody, wu:fa95a05 antibody, zgc:154081 antibody, AIMP1 antibody, 9830137A06Rik antibody, AIMP1/p43 antibody, Emap2 antibody, Scye1 antibody, scye1 antibody, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog antibody, AIMP1 antibody, aimp1 antibody, Aimp1 antibody, aimp1.S antibody
    背景
    EMAPII is a proinflammatory cytokine and chemoattractant of macrophages. The 20 kDa mature peptide binds to endothelial cells and leukocytes like macrophages. EMAP II activates endothelial cells, by elevation of cytosolic free calcium concentration, release of von Willebrand factor, induction of tissue factor, and expression of adhesion molecules E-selectin and P-selectin. It further activates resting monocytes by elevating cytosolic free calcium concentration, inducing TNFalpha and tissue factor and stimulating chemotaxis. EMAP II has been shown in a tumor model to sensitize the local tumor vasculature to the action of TNFalpha, rendering resistant tumors sensitive to immunotherapy by TNFalpha.Synonyms: AIMP1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, EMAP-2, EMAP-II, Endothelial monocyte-activating polypeptide 2, Endothelial monocyte-activating polypeptide II, Multisynthase complex auxiliary component p43, Small inducible cytokine subfamily E member 1
    基因ID
    9255
    NCBI登录号
    NP_001135887
    UniProt
    Q12904
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