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SFTPD 抗体 (Conformational Domain) (Biotin)

SFTPD 适用: 人, 大鼠 WB, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal IIE11 Biotin
产品编号 ABIN111975
发货至: 中国
  • 抗原 See all SFTPD 抗体
    SFTPD (Surfactant Protein D (SFTPD))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Conformational Domain
    适用
    • 52
    • 21
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 52
    • 17
    小鼠
    克隆类型
    • 52
    • 17
    单克隆
    标记
    • 34
    • 14
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFTPD antibody is conjugated to Biotin
    应用范围
    • 54
    • 32
    • 20
    • 10
    • 8
    • 8
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    II E11 recognizes a conformational epitope of SP-D. No cross reactivity with rat SP-A. Antigen distribution: Tissue sections: alveolar type II cells, alveolar macrophages, two types of Clara cells SP-A+ and SP-A-, and extracellular deposits. Alveolar type III cells stain negative. No reaction on rat skin, colon, kidney and liver.
    免疫原
    Purified rat surfactant protein D from bronchoalveolar lavage
    克隆位点
    IIE11
    亚型
    IgG2b
    Top Product
    Discover our top product SFTPD Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections (1 μg/mL, 1: 400). Immunohistochemistry on paraffin sections (1: 100 freshly prepared for staining rat tissues. Fixation: Acetone 5 min 4 C, paraformaldehyde / paraffin. Tissue pretreatment: microwave treatment 2 x 5 min at 750 W). Western Blot. Suggested positive control: Rat lung.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore by adding 0.5 mL distilled water.
    浓度
    0.4 mg/mL
    缓冲液
    Phosphate buffered saline pH 7.2, (PBS), 5 mg/mL bovine serum albumin (BSA) as a stabilizer, no preservative.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C for longer.
  • Bräuer, Kindler, Jäger, Sel, Nölle, Pleyer, Ochs, Paulsen: "Detection of surfactant proteins A and D in human tear fluid and the human lacrimal system." in: Investigative ophthalmology & visual science, Vol. 48, Issue 9, pp. 3945-53, (2007) (PubMed).

  • 抗原
    SFTPD (Surfactant Protein D (SFTPD))
    别名
    SFTPD (SFTPD 产品)
    别名
    COLEC7 antibody, PSP-D antibody, SFTP4 antibody, SP-D antibody, BDE antibody, BDSD antibody, HOX4I antibody, SPD antibody, AI573415 antibody, Sftp4 antibody, surfactant protein D antibody, homeobox D13 antibody, surfactant associated protein D antibody, SFTPD antibody, HOXD13 antibody, Sftpd antibody, SP-D antibody
    背景
    Surfactant protein D (SP-D) is a Ca2+-dependent carbohydrate-binding protein and is structurally similar to other C-type mammalian lectins, such as conglutinin and SP-A. It has a molecular size of approximately 43 kDa in its reduced state, 620 kDa in non-dissociating conditions. SP-D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SP-A, which is the most abundant surfactant protein. SP-D is synthesized and secreted by alveolar epithelial type II cells.Synonyms: COLEC7, Collectin-7, Lung surfactant protein D, PSP-D, PSPD, Pulmonary surfactant-associated protein D, SFTP4, SP-D
    基因ID
    25350
    NCBI登录号
    NP_037010
    UniProt
    P35248
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