(1 reference)-
- 抗原 See all CD93 抗体
- CD93
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD93 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This Monoclonal antibody clone X-2 recognizes a 110 kDa O-sialoglycoprotein on granulocytes, monocytes and endothelial cells. Upon differentiation of cultivated monocytes into macrophages, CDw93 ceases to be expressed on day 5-6, which makes it a very useful marker to differentiate those two cell populations. Antigen Distribution Isolated Cells: Positive with all granulocytes, with staining increasing transiently upon maturation. Antigen expression is increased by TNFα, GM-CSF, (fMLP) treatment. No effect on superoxide production by binding to neutrophils has been noted. PMA stimulation causes down regulation of the antigen. Positive with monocytes following fMLP, TNF, GM-CSF treatment. Antigen expression decreases on cultured monocytes. Positive on AML cases with monocytic component. Positive on cell lines HL-60, Namalva, K562, THP-1, U937, negative on HMC-1 (human mast cell line). Tissue Sections: The Monoclonal antibody X-2 stains epitheloid cells and Rosai-Dorfman cells and most endothelial cells in the synovial membrane of RA patients.
- 纯化方法
- Affinity Chromatography
- 免疫原
- Human monocytes. Remarks: The antigen has been assigned to the CDw93 cluster, the epitope has not been further characterized.
- 克隆位点
- X-2
- 亚型
- IgG1
- Top Product
- Discover our top product CD93 Primary Antibody
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anti-CD93 (CD93) (AA 474-535) antibody
CD93 适用: 人 IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1A10E10 unconjugated
anti-CD93 (CD93) (AA 474-535) antibodyCD93 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2F7D11 unconjugated
anti-CD93 (CD93) (AA 82-369) antibodyCD93 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD93 (CD93) antibodyCD93 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal mNI-11 unconjugated
anti-CD93 (CD93) (AA 227-493) antibodyCD93 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD93 (CD93) (AA 33-140) antibodyCD93 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A4 unconjugated
anti-CD93 (CD93) antibodyCD93 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 小鼠 Monoclonal VIMD2 unconjugated
anti-CD93 (CD93) (C-Term) antibodyCD93 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD93 (CD93) antibody (FITC)CD93 适用: 人 FACS 宿主: 小鼠 Monoclonal VIMD2 FITC
anti-CD93 (CD93) antibody (PE)CD93 适用: 人 FACS 宿主: 小鼠 Monoclonal VIMD2 PE
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- 应用备注
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Suitable for Immunohistochemistry (IHC) on: Frozen sections: 0.5 μg/mL (1/400)Paraffin sections: does not react on routinely processedparaffin sections. It works alos in FACS. Suggested positive control: human tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 0.5 mL distilled water
- 浓度
- 0.2 mg/mL
- 缓冲液
- PBS, pH 7.2, 0.01 % Thimerosal, 10 mg/mL BSA
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody at 2-8 °C before reconstitution. After reconstitution store at 2-8° for up to 2 months. DO NOT FREEZE. Recontstituted product is stable for 2 days at RT.
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: "A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells." in: Nature communications, Vol. 9, Issue 1, pp. 2202, (2018) (PubMed).
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: "A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells." in: Nature communications, Vol. 9, Issue 1, pp. 2202, (2018) (PubMed).
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- 抗原
- CD93
- 别名
- CD93 / C1QR1 (CD93 产品)
- 背景
- CD93 a cell-surface glycoprotein and type I membrane protein involve in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.Synonyms: C1q receptor, C1q/MBL/SPA receptor, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, MBL receptor, MXRA4, Matrix-remodeling-associated protein 4, SPA receptor
- 基因ID
- 22918
- NCBI登录号
- NP_036204
- UniProt
- Q9NPY3
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