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SFTPD 抗体 (Lectin Domain) (Biotin)

The 小鼠 单克隆 anti-SFTPD antibody is suitable to detect SFTPD in samples from 人 和 大鼠. It has been validated for WB, IHC (fro) 和 EIA.
产品编号 ABIN111842
发货至: 中国
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Quick Overview for SFTPD 抗体 (Lectin Domain) (Biotin) (ABIN111842)

抗原

See all SFTPD 抗体
SFTPD (Surfactant Protein D (SFTPD))

适用

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人, 大鼠

宿主

  • 51
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小鼠

克隆类型

  • 50
  • 24
单克隆

标记

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This SFTPD antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

VIF11
  • 抗原表位

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    Lectin Domain

    特异性

    Antigen Distribution on Tissue Sections: alveolar type II cells, alveolar macrophages, two types of Clara cells SP-A+ and SP-A-, and extracellular deposits. Alveolar type III cells stain negative. No reaction on Rat skin, colon, kidney and liver.

    纯化方法

    Affinity Chromatography

    免疫原

    Purified rat surfactant protein D from bronchoalveolar lavage. Remarks: The antigen epitope is localized in the Lectin domain of SP-D.

    亚型

    IgG1
  • 应用备注

    Immunohistochemistry (IHC) on Frozen sections (2 μg/mL (1/200) for rat cryosections) andParaffin sections. ELISA. Western Blots. Suggested positive control: Rat lung.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 0.5 mL distilled water.

    浓度

    0.4 mg/mL

    缓冲液

    PBS, pH 7.2, 10 mg/mL BSA as a stabilizer and 0.01 % Thimerosal as a preservative

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • 抗原

    SFTPD (Surfactant Protein D (SFTPD))

    别名

    SFTPD

    背景

    Surfactant protein D (SP-D) is a Ca2+-dependent carbohydrate-binding protein and is structurally similar to other C-type mammalian lectins, such as conglutinin and SP-A. It has a molecular size of approximately 43 kDa in its reduced state, 620 kDa in non-dissociating conditions. SP-D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SP-A, which is the most abundant surfactant protein. SP-D is synthesized and secreted by alveolar epithelial type II cells.Synonyms: COLEC7, Collectin-7, Lung surfactant protein D, PSP-D, PSPD, Pulmonary surfactant-associated protein D, SFTP4, SP-D

    基因ID

    25350

    NCBI登录号

    NP_037010

    UniProt

    P35248
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