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SFTPD 抗体 (Lectin Domain)

SFTPD 适用: 人, 大鼠 WB, IHC (p), IHC (fro), EIA 宿主: 小鼠 Monoclonal VIF11 unconjugated
产品编号 ABIN111841
发货至: 中国
  • 抗原 See all SFTPD 抗体
    SFTPD (Surfactant Protein D (SFTPD))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Lectin Domain
    适用
    • 52
    • 21
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 52
    • 17
    小鼠
    克隆类型
    • 52
    • 17
    单克隆
    标记
    • 33
    • 15
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFTPD antibody is un-conjugated
    应用范围
    • 54
    • 32
    • 20
    • 10
    • 8
    • 8
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    Clone VI F11 is useful for staining rat and human surfactant protein D . Antigen Distribution on Tissues and Cells: Alveolar type II cells, alveolar macrophages, two types of Clara cells SP-A+ and SP-A-, and extracellular deposits. Alveolar type III cells stain negative. No reaction on Rat skin, colon, kidney and liver.
    交叉反应 (详细)
    Species reactivity (tested):Rat and Human. Negative with Pig
    纯化方法
    Affinity Chromatography
    免疫原
    Purified Rat Surfactant Protein D (SP-D) from bronchoalveolar lavage. Remarks: The epitope is localized in the lectin domain of SP-D.
    克隆位点
    VIF11
    亚型
    IgG1
    Top Product
    Discover our top product SFTPD Primary Antibody
  • 应用备注
    Immunohistochemistry on Frozen Sections: 0.5 μg/mL (1/800) for Rat Cryosections and10-20 μg/mL (1/20-1/40) for Human Frozen Sections. Immunohistochemistry on Paraffin Sections: 10-20 μg/mL (1/20-1/40) for Rat paraffinsections (microwave pretreatment for antigen retrieval is recommended). Suggested Positive Control: Rat lung. Has been described to work in ELISA and Western blots.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore by adding 0.5 mL distilled water (= 0.4 mg/mL Stock Solution).
    浓度
    0.4 mg/mL
    缓冲液
    Stock solution contains PBS, pH 7.2 with 0.09 % Sodium Azide as preservative and 5 mg/mL BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.
  • 抗原
    SFTPD (Surfactant Protein D (SFTPD))
    别名
    SFTPD (SFTPD 产品)
    别名
    COLEC7 antibody, PSP-D antibody, SFTP4 antibody, SP-D antibody, BDE antibody, BDSD antibody, HOX4I antibody, SPD antibody, AI573415 antibody, Sftp4 antibody, surfactant protein D antibody, homeobox D13 antibody, surfactant associated protein D antibody, SFTPD antibody, HOXD13 antibody, Sftpd antibody, SP-D antibody
    背景
    Surfactant protein D is a Ca2+ -dependent carbohydrate binding protein with a similar structure as other C-type mammalian lectins such as conglutinin and SP-A. The molecular weight is 620 kD under non reducing conditions and 43 kD under reducing conditions. The function of SP-D is not clearly defined. SP-D enhances the production of oxygen radicals in alveolar macrophages and regulates some actions of SP-A, which is the most abundant surfactant protein. SP-D is synthesized and secreted by alveolar epithelial type II cells.Synonyms: COLEC7, Collectin-7, Lung surfactant protein D, PSP-D, PSPD, Pulmonary surfactant-associated protein D, SFTP4, SP-D
    基因ID
    25350
    NCBI登录号
    NP_037010
    UniProt
    P35248
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