CRH 抗体
Quick Overview for CRH 抗体 (ABIN111808)
抗原
See all CRH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific for corticotrophin releasing factor (CRF), a hormone found mainly in the hypothalamus that regulates the release of corticotrophin from the pituitary gland. The unique lysine residue (Lys-36) is likely to be involved in the antigenic determinant as lysine modification by CA blocks binding completely. Human serum, containing CRF-binding protein, also inhibits the binding of this antibody to CRF.Aff. Const.:10(e)-9 M with native and modified CRF
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Corticotrophin Releasing Factor conjugated to Bovine Serum Albumin.
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亚型
- IgG1
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anti-Corticotropin Releasing Hormone (CRH) (AA 40-195) antibody
CRH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 154-196) antibodyCRH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Corticotropin Releasing Hormone (CRH) (N-Term) antibodyCRH 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 39-187) antibodyCRH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) antibodyMicroarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB701026 unconjugated
anti-Corticotropin Releasing Hormone (CRH) antibodyMicroarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB189288 unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 185-196) antibodyCRH 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) antibodyMicroarray verified CRH 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB561789 unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 25-194) antibodyCRH 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Corticotropin Releasing Hormone (CRH) (AA 29-45) antibodyCRH 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on Frozen sections. Immunohistochemistry on Paraffin sections: 1/100 - 1/7000, Microwave pretreatment isrequired. Enzyme digestion with 0.1 % trypsin may also be necessary. ELISA: This antibody is suitable for use in a sandwich ELISA with clone 5D5 (BM356).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CRH (Corticotropin Releasing Hormone (CRH))
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别名
- Corticoliberin
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背景
- CRF precursor is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRF is a neuroendocrine hormone secreted by the paraventricular nucleus (PVN) of the hypothalamus and is a key player in the hypothalamic pituitary adrenal axis. It is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. Neuronal CRF is important in a variety of diverse roles including, memory, depression, stress, kidney function, parturition, metabolism and feeding (to mention a few).Synonyms: CRF, CRH, Corticotropin-Releasing Factor, Corticotropin-Releasing Hormone
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基因ID
- 1392
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NCBI登录号
- NP_000747
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UniProt
- P06850
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
抗原
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