Neisseria Gonorrhoeae 抗体
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Quick Overview for Neisseria Gonorrhoeae 抗体 (ABIN111570)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G chromatography.
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免疫原
- Pool of UV-inactivated N. gonorrhoeae cells. Neisseria Reference Laboratory strains G-7, R-11 and 71222 (W-I), 5766 and 8038 (W-II), 8660 (W-III).
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亚型
- IgG2b
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应用备注
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Suitable for use in ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.52 mg/mL (OD280 nm)
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缓冲液
- PBS buffer, pH 7.4, without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Neisseria Gonorrhoeae
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物质类
- Bacteria
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背景
- Neisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn).
抗原
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