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beta Endorphin 抗体

beta-EP 适用: 人 IHC (fro), IF, IHC (p) 宿主: 小鼠 Monoclonal B31-15 unconjugated
产品编号 ABIN111318
发货至: 中国
  • 抗原 See all beta Endorphin (beta-EP) 抗体
    beta Endorphin (beta-EP) (Endorphin beta (beta-EP))
    适用
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    宿主
    • 17
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    小鼠
    克隆类型
    • 16
    • 4
    单克隆
    标记
    • 17
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    This beta Endorphin antibody is un-conjugated
    应用范围
    • 11
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    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein A affinity chromatography
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human beta-endorphin (full length native protein)
    克隆位点
    B31-15
    亚型
    IgG1
    Top Product
    Discover our top product beta-EP Primary Antibody
  • 应用备注
    Immunohistochemistry (paraffin sections): 10 - 20 mg/mL. Staining technique: Standard ABC technique (DAB+). Pretreatment: Heat retrieval (microwave oven). Incubation: overnight at 4 C. Positive tissue: Human pituitary gland. Immunohistochemistry (frozen sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Dilute only prior to immediate use
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Millenbaugh, Baskin, DeSilva, Elliott, Glickman: "Photothermal killing of Staphylococcus aureus using antibody-targeted gold nanoparticles." in: International journal of nanomedicine, Vol. 10, pp. 1953-60, (2016) (PubMed).

    Fröbel, Cadeddu, Hartwig, Bruns, Wilk, Kündgen, Fischer, Schroeder, Steidl, Germing, Lehr, Haas, Czibere: "Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1272-80, (2013) (PubMed).

    Meier, Köhler, Alkhatib, Sergi, Junker, Klein, Schmidt, Fritsch: "Beta-cell development and turnover during prenatal life in humans." in: European journal of endocrinology, Vol. 162, Issue 3, pp. 559-68, (2010) (PubMed).

    Ubuka, Lai, Kitani, Suzuuchi, Pham, Cadigan, Wang, Chowdhury, Tsutsui, Bentley: "Gonadotropin-inhibitory hormone identification, cDNA cloning, and distribution in rhesus macaque brain." in: The Journal of comparative neurology, Vol. 517, Issue 6, pp. 841-55, (2009) (PubMed).

    Stenholm, Hakanen, Vaarno, Pihlasalo, Terho, Hänninen, Vuopio-Varkila, Huovinen, Kotilainen: "Methicillin-resistant Staphylococcus aureus screening by online immunometric monitoring of bacterial growth under selective pressure." in: Antimicrobial agents and chemotherapy, Vol. 53, Issue 12, pp. 5088-94, (2009) (PubMed).

    Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: "A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA." in: Hybridoma, Vol. 10, Issue 3, pp. 379-86, (1991) (PubMed).

  • 抗原
    beta Endorphin (beta-EP) (Endorphin beta (beta-EP))
    别名
    beta Endorphin (beta-EP 产品)
    别名
    ACTH antibody, BE antibody, Beta-LPH antibody, Clip antibody, Gamma-LPH antibody, Npp antibody, Pomc-1 antibody, Pomc1 antibody, alpha-MSH antibody, alphaMSH antibody, beta-MSH antibody, gamma-MSH antibody, CLIP antibody, LPH antibody, MSH antibody, NPP antibody, POC antibody, pro-opiomelanocortin-alpha antibody, proopiomelanocortin antibody, Pomc antibody, POMC antibody
    背景
    Beta-Endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. Beta-Endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). Beta-Endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the μ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects. Beta-Endorphin occurs in cells in the anterior pituitary. Beta-Endorphin may be detected in tumors of the pituitary, gastroinestinal and bronchial carcinoids. Absorption with 10-100 μg beta-Endorphin per ml diluted antiserum inactivates the antiserum, while Beta-lipotropin, met-enkephalin and leu-enkephalin do not.Synonyms: Endorfin-beta, Endorphin-beta
    途径
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
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