Tubulin B 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 大鼠.
1 image
Quick Overview for Tubulin B 抗体 (ABIN1112941)
抗原
Tubulin B
适用
大鼠
宿主
兔
克隆类型
多克隆
应用范围
Western Blotting (WB)
-
-
纯化方法
- affinity purified
-
亚型
- IgG
-
-
-
应用备注
- WB (1:2000). Other applications have not been tested. The optimal dilutions should be determined by end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
-
储存液
- Sodium azide, Thimerosal (Merthiolate)
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
-
有效期
- 12 months
-
-
- Tubulin B
-
背景
- Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are alpha-tubulin and beta-tubulin, the proteins that make up microtubules. Each has a molecular weight of approximately 55 kiloDaltons. Microtubules are assembled from dimers of alpha- and beta-tubulin. These subunits are slightly acidic with an isoelectric point between 5.2 and 5.8. 1 Mutant huntingtin, disrupted intracellular transport and insulin secretion by direct interference with microtubular beta-tubulin. Mutant huntingtin impaired glucose-stimulated insulin secretion in insulin-producing beta cells, without altering stored levels of insulin. Smith et al. (2009) proposed a novel pathogenetic process by which mutant huntingtin may disrupt hormone exocytosis from beta cells and possibly impair vesicular transport in any cell that expresses the pathogenic protein. 2
抗原
-
You are here:
