YWHAB
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
应用备注
WB (1:1000-2000). Other applications have not been tested. The optimal dilutions should be determined by end user.
限制
仅限研究用
状态
Liquid
缓冲液
TBS (pH7.4), 0.5% BSA, 25% Glycerol and 0.05% Sodium Azide.
储存液
Sodium azide, Thimerosal (Merthiolate)
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
有效期
12 months
抗原
YWHAB
(14-3-3 alpha + beta (YWHAB))
别名
14-3-3 beta / alpha
背景
14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. They have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 100 signaling proteins have been reported as 14-3-3 ligands, 14-3-3 b/a is one of them. They play important roles in a wide range of vital regulatory processes, such as mitogenic signal transduction, apoptotic cell death, and cell cycle control. Elevated amounts of 14-3-3 proteins are found in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.