CD56 抗体
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北京 101111
Quick Overview for CD56 抗体 (ABIN111265)
抗原
See all CD56 (NCAM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with Rhesus Monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
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交叉反应 (详细)
- Species reactivity (tested):Human and non-Human Primates.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- KG-1 Human acute myelogenous leukaemia cell line
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亚型
- IgG2a
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应用备注
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Western Blot. Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50Pretreatment: Heat retrieval (microwave oven) in citrate buffer standard ABC visualization. Positive Tissue: Positive membrane-specific reaction in adjacent peripheral nerve Stainingof paraprostatic autonomic ganglion. Staining technique: Standard ABC technique (DAB+).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 with 15 mM Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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别名
- CD56
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背景
- CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1
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基因ID
- 4684
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NCBI登录号
- NP_000606
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UniProt
- P13591
抗原
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