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PDGFRB 抗体

PDGFRB 适用: 人, 猴 WB, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 21-72 unconjugated
产品编号 ABIN111188
发货至: 中国
  • 抗原 See all PDGFRB 抗体
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    适用
    • 196
    • 87
    • 82
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 猴
    宿主
    • 176
    • 25
    • 2
    • 2
    小鼠
    克隆类型
    • 166
    • 39
    单克隆
    标记
    • 107
    • 10
    • 8
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    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
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    • 4
    • 4
    • 4
    • 4
    • 1
    This PDGFRB antibody is un-conjugated
    应用范围
    • 151
    • 76
    • 54
    • 53
    • 46
    • 33
    • 29
    • 18
    • 16
    • 10
    • 8
    • 4
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    This antibody is specific for the extracellular domain of the PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. This antibody does not recognize PDGF receptor alpha. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Human skin fibroblast cell membrane extracts.
    克隆位点
    21-72
    亚型
    IgG1
    Top Product
    Discover our top product PDGFRB Primary Antibody
  • 应用备注
    Flow Cytometry: 25 μg/mL. Immunoprecipitation. Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: 25 μg/mL. Recommended Positive Control: Human breast cancer tissue.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    别名
    CD140b / PDGFRB (PDGFRB 产品)
    别名
    AI528809 antibody, CD140b antibody, PDGFR-1 antibody, Pdgfr antibody, CD140B antibody, IBGC4 antibody, JTK12 antibody, PDGFR antibody, PDGFR1 antibody, platelet derived growth factor receptor, beta polypeptide antibody, platelet derived growth factor receptor beta antibody, Pdgfrb antibody, PDGFRB antibody
    背景
    PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3.Synonyms: Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, PDGF Receptor beta, PDGF-R-beta
    基因ID
    5159
    NCBI登录号
    NP_002600
    UniProt
    P09619
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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