PRSS1 抗体
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北京 101111
Quick Overview for PRSS1 抗体 (ABIN7101954)
抗原
See all PRSS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human pancreatic trypsin. Recognizes specifically pancreatic trypsin. Does not cross react with Pancreatic Chymotrypsin.
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纯化方法
- Protein G affinity chromatography.
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免疫原
- Purified human pancreatic trypsin
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亚型
- IgG2b
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应用备注
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ELISA: May be used in immunoassays to detect and quantitate Pancreatic Trypsin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL (OD 280 nm)
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缓冲液
- PBS, pH 7.4 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))
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别名
- Trypsin-1 / PRSS1
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背景
- The human pancreas secretes three different isoforms of the inactive trypsinogen into the small intestine, namely cationic trypsinogen, anionic trypsinogen (the two major isoforms) and mesotrypsinogen (a minor isoform). In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3, also known as Trypsin-4, is expressed in the brain in addition to the pancreas.Synonyms: Beta-trypsin, Cationic trypsinogen, Serine protease 1, TRP1, TRY1, TRYP1, Trypsin I
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基因ID
- 5644
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NCBI登录号
- NP_002760
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UniProt
- P07477
抗原
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