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PRSS1 抗体

This anti-PRSS1 antibody is a 小鼠 单克隆 antibody detecting PRSS1 in EIA. Suitable for 人.
产品编号 ABIN7101954
发货至: 中国

Quick Overview for PRSS1 抗体 (ABIN7101954)

抗原

See all PRSS1 抗体
PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

适用

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宿主

  • 59
  • 8
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小鼠

克隆类型

  • 64
  • 5
单克隆

标记

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This PRSS1 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)

克隆位点

401
  • 特异性

    Human pancreatic trypsin. Recognizes specifically pancreatic trypsin. Does not cross react with Pancreatic Chymotrypsin.

    纯化方法

    Protein G affinity chromatography.

    免疫原

    Purified human pancreatic trypsin

    亚型

    IgG2b
  • 应用备注

    ELISA: May be used in immunoassays to detect and quantitate Pancreatic Trypsin.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL (OD 280 nm)

    缓冲液

    PBS, pH 7.4 without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

    别名

    Trypsin-1 / PRSS1

    背景

    The human pancreas secretes three different isoforms of the inactive trypsinogen into the small intestine, namely cationic trypsinogen, anionic trypsinogen (the two major isoforms) and mesotrypsinogen (a minor isoform). In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3, also known as Trypsin-4, is expressed in the brain in addition to the pancreas.Synonyms: Beta-trypsin, Cationic trypsinogen, Serine protease 1, TRP1, TRY1, TRYP1, Trypsin I

    基因ID

    5644

    NCBI登录号

    NP_002760

    UniProt

    P07477
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