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Cardiotrophin 1 抗体

CTF1 适用: 人 ELISA 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN1110877
发货至: 中国
  • 抗原 See all Cardiotrophin 1 (CTF1) 抗体
    Cardiotrophin 1 (CTF1)
    适用
    • 72
    • 23
    • 18
    • 3
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    • 2
    • 2
    • 1
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    宿主
    • 75
    • 5
    • 1
    小鼠
    克隆类型
    • 76
    • 5
    单克隆
    标记
    • 34
    • 13
    • 9
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    This Cardiotrophin 1 antibody is un-conjugated
    应用范围
    • 54
    • 30
    • 28
    • 13
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    • 12
    • 6
    • 5
    • 4
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    • 1
    ELISA
    原理
    Mouse Anti-Human CT1
    产品特性
    Cardiac Markers
    纯化方法
    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen.PurificationThe IgG fraction of tissue culture supernatant was purified by Protein A/G affinity chromatography.
    亚型
    IgG
    Top Product
    Discover our top product CTF1 Primary Antibody
  • 应用备注
    ELISA
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    The antibody is supplied as lyophilized and purified antibody originally containing PBS without any preservatives. Protein amount is indicated on the vial. Reconstitute in de-ionized or distilled water to concentration of 1 mg/mL.
    缓冲液
    PBS
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    -20°C
  • Li, Ma, Wang, Zeng, Li, Kang, Hao: "Exosomal microRNA-141 is upregulated in the serum of prostate cancer patients." in: OncoTargets and therapy, Vol. 9, pp. 139-48, (2016) (PubMed).

  • 抗原
    Cardiotrophin 1 (CTF1)
    别名
    CT1 (CTF1 产品)
    别名
    CTF1 antibody, ct1 antibody, ct-1 antibody, ctf2 antibody, CT-1 antibody, CT1 antibody, cardiotrophin 1 antibody, cardiotrophin-1 antibody, CTF1 antibody, ctf1 antibody, Ctf1 antibody, LOC100736818 antibody
    背景

    Target Description: Cardiotrophin-1 (CT-1, Official gene name: CTF1) is a cardiac hypertrophic factor and belongs to the IL-6 cytokine family. The protein interacts with the glycoprotein 130/leukemia inhibitory factor receptor beta heterodimer. CT-1 deficiency causes increased motoneuron cell death in spinal cord and brainstem nuclei of mice. In addition, CT-1 enhances transcription factor NF kappa B DNA-binding activities and activates phosphatidylinositol 3-kinase in cardiac myocytes. It is also highly expressed in the heart, prostate, skeletal muscle, and ovary, and expressed at the lower levels in lung, kidney, pancreas, thymus, small intestine, and testis. CT-1 is highly secreted by myotubes, and promotes the survival of cultured embryonic mouse and rat MNs. CT-1 is associated with pathophysiology of heart diseases, like hypertension, myocardial infarction, valvular heart disease, and congestive heart failure.

    途径
    JAK/STAT Signaling
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