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IKZF4 抗体 (N-Term)

IKZF4 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109609
发货至: 中国
  • 抗原 See all IKZF4 抗体
    IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
    抗原表位
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 28
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 22
    • 5
    • 1
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IKZF4 antibody is un-conjugated
    应用范围
    • 19
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    NSIKVEMYSD EESSRLLGPD ERLLEKDDSV IVEDSLSEPL GYCDGSGPEP
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat, Dog
    纯化方法
    Purified using Protein A affinity column
    免疫原
    The immunogen for anti-ZNFN1A4 antibody: synthetic peptide directed towards the N terminal of human ZNFN1A4
    Top Product
    Discover our top product IKZF4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Add 100 μL of distilled water to a final concentration of 1 mg/mL.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原
    IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
    别名
    ZNFN1A4 / IKZF4 / EOS (IKZF4 产品)
    别名
    A630026H08Rik antibody, Eos antibody, Zfpn1a4 antibody, Znfn1a4 antibody, EOS antibody, ZNFN1A4 antibody, IKAROS family zinc finger 4 antibody, Ikzf4 antibody, IKZF4 antibody
    背景
    IKZF4 also called ZNFN1A4 is a DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence and acts as transcriptional repressor. It interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2 and may be involved in the development of central and peripheral nervous systems. Highly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.Synonyms: Ikaros family zinc finger protein 4, KIAA1782, Zinc finger protein Eos
    分子量
    64 kDa (585 aa)
    基因ID
    64375
    NCBI登录号
    NP_071910
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