IKZF4 抗体 (N-Term)
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Quick Overview for IKZF4 抗体 (N-Term) (ABIN1109609)
抗原
See all IKZF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NSIKVEMYSD EESSRLLGPD ERLLEKDDSV IVEDSLSEPL GYCDGSGPEP
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat, Dog
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纯化方法
- Purified using Protein A affinity column
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免疫原
- The immunogen for anti-ZNFN1A4 antibody: synthetic peptide directed towards the N terminal of human ZNFN1A4
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 100 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
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别名
- ZNFN1A4 / IKZF4 / EOS
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背景
- IKZF4 also called ZNFN1A4 is a DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence and acts as transcriptional repressor. It interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2 and may be involved in the development of central and peripheral nervous systems. Highly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.Synonyms: Ikaros family zinc finger protein 4, KIAA1782, Zinc finger protein Eos
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分子量
- 64 kDa (585 aa)
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基因ID
- 64375
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NCBI登录号
- NP_071910
抗原
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