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IKZF4 抗体 (N-Term)

This anti-IKZF4 antibody is a 兔 多克隆 antibody detecting IKZF4 in WB. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN1109609
发货至: 中国

Quick Overview for IKZF4 抗体 (N-Term) (ABIN1109609)

抗原

See all IKZF4 抗体
IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 21
  • 5
  • 1

克隆类型

  • 25
  • 2
多克隆

标记

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This IKZF4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 4
    • 2
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    • 1
    • 1
    • 1
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    N-Term

    序列

    NSIKVEMYSD EESSRLLGPD ERLLEKDDSV IVEDSLSEPL GYCDGSGPEP

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat, Dog

    纯化方法

    Purified using Protein A affinity column

    免疫原

    The immunogen for anti-ZNFN1A4 antibody: synthetic peptide directed towards the N terminal of human ZNFN1A4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Add 100 μL of distilled water to a final concentration of 1 mg/mL.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原

    IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))

    别名

    ZNFN1A4 / IKZF4 / EOS

    背景

    IKZF4 also called ZNFN1A4 is a DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence and acts as transcriptional repressor. It interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2 and may be involved in the development of central and peripheral nervous systems. Highly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.Synonyms: Ikaros family zinc finger protein 4, KIAA1782, Zinc finger protein Eos

    分子量

    64 kDa (585 aa)

    基因ID

    64375

    NCBI登录号

    NP_071910
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