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YAF2 抗体 (Middle Region)

This anti-YAF2 antibody is a 兔 多克隆 antibody detecting YAF2 in WB 和 IHC (p). Suitable for 人, 小鼠, 大鼠, 犬, Cow, 小鸡 和 非洲爪蟾.
产品编号 ABIN1109525
发货至: 中国

Quick Overview for YAF2 抗体 (Middle Region) (ABIN1109525)

抗原

See all YAF2 抗体
YAF2 (YY1 Associated Factor 2 (YAF2))

适用

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人, 小鼠, 大鼠, 犬, Cow, 小鸡, 非洲爪蟾

宿主

  • 28
  • 1

克隆类型

  • 29
多克隆

标记

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This YAF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 6
    • 4
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    Middle Region

    序列

    KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK

    交叉反应 (详细)

    Species reactivity (expected):Dog, Rat, Mouse, Bovine, Chicken, African clawed frogSpecies reactivity (tested):Human

    纯化方法

    Purified on Protein A affinity column

    免疫原

    The immunogen for anti-YAF2 antibody: synthetic peptide directed towards the middle region of human YAF2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Add 100 μL of distilled water

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

    有效期

    12 months
  • 抗原

    YAF2 (YY1 Associated Factor 2 (YAF2))

    别名

    YAF2

    背景

    YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.Synonyms: YY1-associated factor 2

    基因ID

    10138

    NCBI登录号

    NP_005739
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