YAF2 抗体 (Middle Region)
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北京 101111
Quick Overview for YAF2 抗体 (Middle Region) (ABIN1109525)
抗原
See all YAF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KGTSTRKPRP VSQLVAQQVT QQFVPPTQSK KEKKDKVEKE KSEKETTSKK
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交叉反应 (详细)
- Species reactivity (expected):Dog, Rat, Mouse, Bovine, Chicken, African clawed frogSpecies reactivity (tested):Human
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纯化方法
- Purified on Protein A affinity column
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免疫原
- The immunogen for anti-YAF2 antibody: synthetic peptide directed towards the middle region of human YAF2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 100 μL of distilled water
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
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有效期
- 12 months
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- YAF2 (YY1 Associated Factor 2 (YAF2))
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别名
- YAF2
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背景
- YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date.Synonyms: YY1-associated factor 2
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基因ID
- 10138
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NCBI登录号
- NP_005739
抗原
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