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Vinculin 抗体

VCL 适用: 人 WB, IHC (fro), EIA 宿主: 小鼠 Monoclonal FB11 unconjugated
产品编号 ABIN1109492
发货至: 中国
  • 抗原 See all Vinculin (VCL) 抗体
    Vinculin (VCL)
    适用
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    宿主
    • 93
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    小鼠
    克隆类型
    • 84
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    单克隆
    标记
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    This Vinculin antibody is un-conjugated
    应用范围
    • 85
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    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    The antibody reacts with the Vinculin antigen. In Immunoblotting the antibody identifies a 130 kDa polypeptide.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Purified
    免疫原
    Purified Vinculin from Human smooth muscle. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
    克隆位点
    FB11
    亚型
    IgG1
    Top Product
    Discover our top product VCL Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azdie, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    Vinculin (VCL)
    Abstract
    VCL 产品
    别名
    CMD1W antibody, CMH15 antibody, MV antibody, MVCL antibody, VCL antibody, im:6902790 antibody, hm:zehn2160 antibody, DDBDRAFT_0186762 antibody, DDBDRAFT_0232320 antibody, DDB_0186762 antibody, DDB_0232320 antibody, 9430097D22 antibody, AA571387 antibody, AI462105 antibody, AW545629 antibody, CG3299 antibody, CT11081 antibody, Dmel\\CG3299 antibody, Dmvincp antibody, EG:103B4.1 antibody, Vin antibody, Vin2EF antibody, vinc antibody, LOC100228062 antibody, vcl-A antibody, vinculin antibody, vinculin a antibody, vinculin A antibody, Vinculin antibody, vinculin S homeolog antibody, VCL antibody, vcla antibody, vinA antibody, Vcl antibody, Vinc antibody, CpipJ_CPIJ013873 antibody, Bm1_37935 antibody, vcl antibody, vcl.S antibody
    背景
    Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and alpha actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix.Synonyms: Metavinculin
    基因ID
    7414
    NCBI登录号
    NP_003364
    UniProt
    P18206
    途径
    Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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