SNF8 抗体 (N-Term)
Quick Overview for SNF8 抗体 (N-Term) (ABIN1109459)
抗原
See all SNF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEF
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交叉反应 (详细)
- Species reactivity (expected):Mouse, Rat, African clawed frog, Bovine, Dog, Chicken, ZebrafishSpecies reactivity (tested):Human
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纯化方法
- Purified on peptide immunoaffinity column
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免疫原
- The immunogen for anti-EAP30 antibody: synthetic peptide directed towards the N terminal of human EAP30
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 50 μL of distilled water
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
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有效期
- 12 months
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- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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别名
- Vacuolar-Sorting Protein SNF8
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背景
- ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25, and VPS36 form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation facto.Synonyms: EAP30, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22
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基因ID
- 11267
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NCBI登录号
- NP_009172
抗原
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