SNF8 抗体 (N-Term)
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- 抗原 See all SNF8 抗体
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, Cow, 犬, 斑马鱼, 非洲爪蟾, 小鸡
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNF8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 序列
- MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEF
- 交叉反应 (详细)
- Species reactivity (expected):Mouse, Rat, African clawed frog, Bovine, Dog, Chicken, ZebrafishSpecies reactivity (tested):Human
- 纯化方法
- Purified on peptide immunoaffinity column
- 免疫原
- The immunogen for anti-EAP30 antibody: synthetic peptide directed towards the N terminal of human EAP30
- Top Product
- Discover our top product SNF8 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- Add 50 μL of distilled water
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
- 有效期
- 12 months
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- 抗原
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- 别名
- Vacuolar-Sorting Protein SNF8 (SNF8 产品)
- 背景
- ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25, and VPS36 form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation facto.Synonyms: EAP30, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22
- 基因ID
- 11267
- NCBI登录号
- NP_009172
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