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SNF8 抗体 (N-Term)

This anti-SNF8 antibody is a 兔 多克隆 antibody detecting SNF8 in WB 和 IHC (p). Suitable for 人, 大鼠, 小鼠, Cow, 犬, 斑马鱼, 非洲爪蟾 和 小鸡.
产品编号 ABIN1109459
发货至: 中国

Quick Overview for SNF8 抗体 (N-Term) (ABIN1109459)

抗原

See all SNF8 抗体
SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

适用

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人, 大鼠, 小鼠, Cow, 犬, 斑马鱼, 非洲爪蟾, 小鸡

宿主

  • 48
  • 2

克隆类型

  • 49
  • 2
多克隆

标记

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This SNF8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 8
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    N-Term

    序列

    MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEF

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, African clawed frog, Bovine, Dog, Chicken, ZebrafishSpecies reactivity (tested):Human

    纯化方法

    Purified on peptide immunoaffinity column

    免疫原

    The immunogen for anti-EAP30 antibody: synthetic peptide directed towards the N terminal of human EAP30
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Add 50 μL of distilled water

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

    有效期

    12 months
  • 抗原

    SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

    别名

    Vacuolar-Sorting Protein SNF8

    背景

    ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25, and VPS36 form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation facto.Synonyms: EAP30, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22

    基因ID

    11267

    NCBI登录号

    NP_009172
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