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TUBB3 抗体

This 小鼠 单克隆 antibody specifically detects TUBB3 in WB, IP, IHC (fro) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN1109374
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TUBB3 抗体 (ABIN1109374)

抗原

See all TUBB3 抗体
TUBB3 (Tubulin, beta 3 (TUBB3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TUBB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

3D9
  • 特异性

    Reacts with Human 55 kDa TUBB3 protein. Cross reacts with Mouse, Rat and other species.

    纯化方法

    Affinity Chromatography on Protein A

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore in distilled water

    浓度

    1 mg/mL

    缓冲液

    PBS, None
  • 抗原

    TUBB3 (Tubulin, beta 3 (TUBB3))

    别名

    TUBB3 / TUBB4

    背景

    Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, α- and β-tubulin, are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

    基因ID

    10381

    途径

    Microtubule Dynamics, M Phase
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