TSHZ3 抗体 (Middle Region)
This 兔 多克隆 antibody specifically detects TSHZ3 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
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产品编号 ABIN1109362
发货至:
中国
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Quick Overview for TSHZ3 抗体 (Middle Region) (ABIN1109362)
抗原
See all TSHZ3 抗体
TSHZ3
(Teashirt Zinc Finger Homeobox 3 (TSHZ3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This TSHZ3 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- Middle Region
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序列
- LNVEVKKEVD KEKAVTDEKP KQKDKPGEEE EKCDISSKYH YLTENDLEES
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交叉反应 （详细）
- Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human
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纯化方法
- Purified using peptide immunoaffinity column
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免疫原
- The immunogen for anti-ZNF537 antibody: synthetic peptide directed towards the middle region of human ZNF537.
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anti-Teashirt Zinc Finger Homeobox 3 (TSHZ3) (AA 466-515) antibody
TSHZ3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
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别名
- TSHZ3 / ZNF537
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背景
- TSHZ3 is a transcriptional regulator involved in developmental processes. It function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. TSHZ3 associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) and regulates the development of neurons involved in both respiratory rhythm and airflow control. It promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. TSHZ3 ot ZNF537 is involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes and in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.Synonyms: KIAA1474, TSH3, Teashirt homolog 3, Zinc finger protein 537
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基因ID
- 57616
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NCBI登录号
- NP_065907
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途径
- Regulation of Muscle Cell Differentiation
抗原
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