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TSFM 抗体 (N-Term)

This anti-TSFM antibody is a 兔 多克隆 antibody detecting TSFM in WB 和 IHC (p). Suitable for 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼 和 非洲爪蟾.
产品编号 ABIN1109361
发货至: 中国
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Quick Overview for TSFM 抗体 (N-Term) (ABIN1109361)

抗原

See all TSFM 抗体
TSFM (Ts Translation Elongation Factor, Mitochondrial (TSFM))

适用

  • 41
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人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 非洲爪蟾

宿主

  • 39
  • 3

克隆类型

  • 25
  • 17
多克隆

标记

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This TSFM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    N-Term

    序列

    KQAEIWLHKE AQKEGWSKAA KLQGRKTKEG LIGLLQEGNT TVLVEVNCET

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat, Dog, African clawed frog, Bovine, ZebrafishSpecies reactivity (tested):Human

    纯化方法

    Purified using peptide immunoaffinity column

    免疫原

    The immunogen for anti-TSFM antibody: synthetic peptide directed towards the N terminal of human TSFM.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Add 50 μL of distilled water to a final concentration of 1 mg/mL.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原

    TSFM (Ts Translation Elongation Factor, Mitochondrial (TSFM))

    别名

    TSFM

    背景

    The TSFM gene encodes a protein that is expressed in all tissues, with the highest levels of expression in skeletal muscle, liver, and kidney. It associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Defects in TSFM are the cause of combined oxidative phosphorylation deficiency type 3 (COXPD3). Defects in the mitochondrial oxidative phosphorylation system result in devastating, mainly multisystem, diseases. COXPD3 symptoms include severe metabolic acidosis with encephalomyopathy or with hypertrophic cardiomyopathy. Patients show a severe defect in mitochondrial translation leading to a failure to assemble adequate amounts of three of the oxidative phosphorylation complexesSynonyms: EF-Ts, EF-TsMt, Elongation factor Ts mitochondrial

    基因ID

    10102

    NCBI登录号

    NP_005717
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